Sort   by:  
 Page size 
Rapid advances in the fields of DNA-, RNA-, polypeptide-sequencing and metabolomics have markedly enhanced our understanding of fundamental biological processes. In contrast to other post-translational modifications (PTMs), the most abundant PTM, glycosylation, remains largely unexplored at the prot...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-09-25 | PXD005804 | Pride
Metronidazole (Metro) represents the front line-drug against Helicobacter pylori infections, but despite its crucial role as an antibiotic, little is known about its exact mode of action (MoA). To unravel cellular protein targets, we here performed activity-based protein profiling (ABPP) with tailor...
ORGANISM(S): Helicobacter pylori 26695 
2026-04-13 | PXD051773 | Pride
Helicobacter pylori γ-glutamyltransferase (gGT) is a conserved virulence factor promoting bacterial colonization and immune tolerance. Although some studies addressed potential mechanisms explaining its function, the supportive role of gGT for in-vivo colonization remains unclear. In addition, it is...
ORGANISM(S): Helicobacter pylori PMSS1 Helicobacter pylori G27 
2025-04-08 | PXD050334 | Pride
Isoquinolines (IQs) are natural substances with antibiotic potential. IQ-238 is a synthetic analog of the novel-type N,C-coupled naphtylisoquinoline (NIQ) alkaloid ancisheynine. Gene expression data, cytotoxicity measurements and metabolic modelling is combined to assess the effects of the N,C-coup...
ORGANISM(S): Staphylococcus aureus 
Sort   by:  
 Page size