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ProteomicsProtein expression in the prefrontal cortex of aged mice with progranulin deficiency or neuronal progranulin overexpression
Description: Progranulin deficiency is associated with neurodegeneration in humans and in mice. We performed a deep proteomic screen of the pre-frontal cortex in aged (13-15 months) female progranulin-deficient mice (GRN-/-) and mice with a neuron-specific inducible overexpression of progranulin (SL...
ORGANISM(S): Mus musculus (Mouse) 
2016-10-13 | PXD004087 | Pride
Lc-ms/ms Mice Cortex Progranulin Neurodegeneration 
TranscriptomicsGenome-wide comparison between IL-17 and combined TNF-alpha/ IL-17 induced genes in primary murine hepatocytes
Cytokines such as TNF-alpha and IL-1beta are known for their contribution to inflammatory processes in liver . In contrast, the cytokine IL-17 has not yet been assigned a role in liver diseases. IL-17 can cooperate with TNF-alpha to induce a synergistic response on several target genes in different ...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-19272 | biostudies-arrayexpress
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