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ProteomicsChinese hamster ovary (CHO) cell Surfaceome LC-MSMS and mRNA expression analysis
The production of biopharmaceuticals relies on robust cell systems that can produce recombinant proteins at high levels, and grow and survive in the stressful bioprocess environment. Chinese hamster ovary cells (CHO) as the main production hosts offer a variety of advantages including robust growth ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2022-10-15 | PXD033581 | Pride
Lc-msms Signaling pathways Mrna expression Cho cells Surfaceome 
ProteomicsMulti-omics analysis reveals the impact of influenza A virus host adaptation on immune signatures in pig tracheal tissue
Influenza A virus (IAV) infection is a global respiratory disease, which annually leads to 3-5 million cases of severe illness, resulting in 290,000-650,000 deaths. Additionally, during the past century, four global IAV pandemics have claimed millions of human lives. The epithelial lining of the tra...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-08-08 | PXD052229 | Pride
Immune regulation Influenza a virus Global proteomics Host adaptation Rna-seq Host metabolism 
ProteomicsAlternative splicing of Arabidopsis G6PD5 can recruits the NADPH-producing OPPP reactions to the endoplasmic reticulum
Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the oxidative pentose-phosphate pathway (OPPP). The OPPP mainly provides NADPH and sugar-phosphate building blocks for anabolic pathways and is present in all eukaryotes. In plant cells, the irreversible part of the OPPP is found in se...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2022-07-11 | PXD035221 | JPOST Repository
TranscriptomicsRNA-seq of Candida albicans cells of the wildtype strain SC5314 and a sky2 deletion mutant grown on different carbon sources (glucose, malic acid, succinic acid)
RNA-sequencing was performed to investigate the role of the Candida albicans protein kinase Sky2 in metabolic adaptation to alternative carbon sources. The Candida albicans wildtype strain SC5314 and a sky2 deletion mutant were grown in medium with either glucose (3h), malic acid (6h) or succinic ac...
ORGANISM(S): Candida albicans 
2026-04-01 | E-MTAB-16222 | biostudies-arrayexpress
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