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MetabolomicsConnecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography
Our understanding of metabolic interactions between small symbiotic animals and bacteria or parasitic eukaryotes that reside within their bodies is extremely limited. This gap in knowledge originates from a methodological challenge, namely to connect histological changes in host tissues induced by b...
2021-07-06 | MTBLS2639 | MetaboLights
MetabolomicsNeuroactive metabolites and bile acids are altered in extremely premature infants with brain injury

The gut microbiome has been associated with pathological neurophysiological evolvement in extremely premature infants suffering from brain injury. The exact underlying mechanism and its associated metabolic signatures in infants are not fully understood. To decipher metab...

2023-12-30 | MTBLS7560 | MetaboLights
UnknownBasic-zipper-type transcription factor FlbB controls asexual development in Aspergillus nidulans.
Not available
S-EPMC2224158 | biostudies-literature
ProteomicsGlycoproteomics reveals the presence of decorin peptides with anti-myostatin activity in human atrial fibrillation
We analysed by proteomics the cardiac extraceelular matrix in human atrial fibrillation and disvovered the presence of extracellular matrix protein fragments that can regulate cardiac cell physiology
ORGANISM(S): Homo sapiens (Human) 
2016-09-29 | PXD004465 | Pride
Atrial fibrillation Human Extracellular matrix 
UnknownReliability, Validity, and Responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO©) Scores in Influenza-Positive Patients.
Not available
S-EPMC5831548 | biostudies-literature
ProteomicsTherapeutic miR-132 inhibition reverses heart failure
Despite some success of pharmacotherapies targeting primarily neurohormonal dysregulation, heart failure is a growing global pandemic with increasing burden. Treatments that improve the disease by reversing heart failure at the cardiomyocyte level are lacking. MicroRNAs (miRNA) are transcriptional r...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-01-09 | PXD015337 | Pride
Calcium cycling/excitation-contraction coupling Translational studies Myocardial biology Myocardial infarction Contractile function 
ProteomicsR. etli CFN42 proteomes showed isoenzymes in free-living and symbiosis with a different transcriptional regulation inferred from a transcriptional regulatory network
Abstract A comparative proteomic study at 6 h of growth in minimal medium (MM) and bacteroids at 18 days of symbiosis of Rhizobium etli CFN42 with the Phaseolus vulgaris leguminous plant was performed. A gene ontology classification of proteins in MM and bacteroid, showed 31 and 10 pathways with hig...
ORGANISM(S): Rhizobium etli CFN 42 
2022-09-27 | PXD035204 | Pride
Lc-ms/ms Transcriptional Network Rhizobium Regulation 
ProteomicsSchizophrenia and nicotine proteomics
Schizophrenia (SCHZ) and tobacco misuse comorbidity is frequently established during adolescence. However, comorbidity markers are still missing. Here, we used an label free quantitative proteomics approach to identify exclusively deregulated proteins in male and female mice modeled to SCHZ with a h...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD043626 | Pride
Prodrome. Psychiatric disorder  nicotine addiction  proteome  comorbidity  e-cigarette  mass spectrometry 
UnknownSingle-Cell, Single-Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity.
Not available
S-EPMC8948611 | biostudies-literature
UnknownPerformance of the inFLUenza Patient-Reported Outcome (FLU-PRO) diary in patients with influenza-like illness (ILI).
Not available
S-EPMC5863969 | biostudies-literature
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