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ProteomicsSmell of Infection: a novel, non-invasive method for detection of fish excretory- secretory proteins
Chemical signals are produced by aquatic organisms following predatory attacks or perturbations such as parasitic infection. Ectoparasites feeding on host fish are likely to cause release of similar alarm cues into the environment due to the stress, wounding and immune response stimulated upon infec...
ORGANISM(S): Kryptolebias marmoratus 
2019-01-02 | PXD010987 | Pride
Gel free ms Alarm cues Parasitic infection 
TranscriptomicsTranscriptomic profiling permits the identification of pollutant sources and effects in ambient water samples
The delta smelt (Hypomesus transpacificus) is a pelagic fish species endemic to the Sacramento-San Joaquin Estuary in Northern California, listed as endangered under both the USA Federal and Californian State Endangered Species Acts and acts as an indicator of ecosystem health in its habitat range. ...
ORGANISM(S): Hypomesus transpacificus 
2012-09-20 | E-GEOD-40991 | biostudies-arrayexpress
TranscriptomicsComparison of DPY-27 binding in embryos and fed L1 larvae
Here we exploit the essential process of X-chromosome dosage compensation to elucidate basic mechanisms that control the assembly, genome-wide binding, and function of gene regulatory complexes that act over large chromosomal territories. We demonstrate that a subunit of C. elegans MLL/COMPASS, a g...
ORGANISM(S): Caenorhabditis elegans 
2011-03-01 | E-GEOD-25877 | biostudies-arrayexpress
TranscriptomicsFed L1 larvae total RNA levels by microarray
Here we exploit the essential process of XM-bM-^@M-^Pchromosome dosage compensation to elucidate basic mechanisms that control the assembly, genomeM-bM-^@M-^Pwide binding, and function of gene regulatory complexes that act over large chromosomal territories. We demonstrate that a subunit of C. ele...
ORGANISM(S): Caenorhabditis elegans 
2011-03-01 | E-GEOD-25831 | biostudies-arrayexpress
GenomicNeoadjuvant Trastuzumab Response in Breast Cancer

HER2 (ERBB2) gene amplification and overexpression are present in 15-30% of invasive breast cancers. While HER2-targeted agents such as trastuzumab are effective treatments, therapeutic resistance remains a concern in HER2-positive breast cancer with 40-50% of patients having residual disease aft...

phs001291 | dbGaP
TranscriptomicsTotal RNA-sequencing Detects Transcriptome Differences in Mouse Preosteoblast Response to Bulk Nanostructured Titanium
Titanium is the most widely used alloy family in dental and orthopedic implants due to its natural ability to integrate into bone, but cytotoxic alloying elements are required in titanium for its mechanical properties to match the functionality of natural bone in high-load bearing applications. Rece...
ORGANISM(S): Mus musculus 
2020-01-02 | E-MTAB-7528 | biostudies-arrayexpress
UnknownSpecies recovery and recolonization of past habitats: lessons for science and conservation from sea otters in estuaries.
Not available
S-EPMC6910117 | biostudies-literature
ProteomicsiTRAQ Manatee
In 2013, two large-scale Florida manatee (Trichechus manatus latirostris) mortality episodes were reported on separate coasts of Florida. The east coast mortality episode was associated with an unknown etiology in the Indian River Lagoon (IRL). The west coast mortality episode was attributed to a pe...
ORGANISM(S): Trichechus manatus (Caribbean manatee) (West Indian manatee) 
2021-08-30 | PXD002470 | Pride
Itraq mass spectrometry Manatee 
TranscriptomicsTranscriptomics evaluation of hexavalent chromium toxicity in human dermal fibroblasts
Significant occupational and environmental exposures to hexavalent chromium, a metal with broad toxicity potential in humans, have been reported. In order to understand the mechanisms of dermal toxicity induced by hexavalent chromium, global gene expression profiling of human dermal fibroblasts expo...
ORGANISM(S): Homo sapiens 
2011-07-30 | E-GEOD-16349 | biostudies-arrayexpress
TranscriptomicsBlood gene expression profile of control and crystalline silica exposed rats
The present research aimed to investigate peripheral blood gene expression profiling as a minimally invasive surrogate approach to study silica-induced pulmonary toxicity. Rats were exposed to crystalline silica by inhalation (15 mg/m3, 6 hours/day, 5 days). Pulmonary damage and blood gene expressio...
ORGANISM(S): Rattus norvegicus 
2011-12-02 | E-GEOD-27023 | biostudies-arrayexpress
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