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TranscriptomicsComparative Genomic Analysis of Clinical Strains of Campylobacter jejuni from South Africa
Background. The bacterial foodborne pathogen Campylobacter jejuni is a common cause of acute gastroenteritis and is also associated with the postinfectious neuropathies, Guillain-Barré and Miller Fisher syndromes. This study described the use of multilocus sequence typing and DNA microarrays to e...
ORGANISM(S): Campylobacter jejuni 
2010-05-27 | E-GEOD-9862 | biostudies-arrayexpress
MetabolomicsMulti-omic responses of mouse liver and skeletal muscle to chronic alcohol drinking

The aim of this study was to define and compare the molecular blueprints of chronic alcohol use in the liver and skeletal muscle using an established pre-clinical mouse model.

2025-12-11 | MTBLS12616 | MetaboLights
ProteomicsHuman Uterine Smooth Muscle S-nitrosoproteome
S-nitrosoproteome of human unterine smooth muscle in different states of pregnancy (Labor, non labor, and preterm labor). Samples were isolated by the biotin switch and streptavidin pulldown before being analyzed by MS/MS on an Orbitrap instrument. Database Searching and bioinformatics: Tandem mas...
ORGANISM(S): Homo sapiens (Human) 
2014-03-02 | PXD000226 | Pride
Human Pregnancy Myometrium S-nitrosation Preterm labor 
TranscriptomicsmicroRNA profiling of Sprague Dawley organs
We performed deep sequencing of the miRNAs present in ~20 toxicologically relevant tissues in Sprague Dawley rats and used three independent analysis of the data to determine which miRNAs are tissue specific and tissue enriched. We performed deep sequencing of miRNAs in 21 organs from 5 male Sprague...
ORGANISM(S): Rattus norvegicus 
2016-09-01 | E-GEOD-78031 | biostudies-arrayexpress
ProteomicsObesity-mediated regulation of the cardiac acetylome
Lysine residues undergo diverse and reversible post-translational modifications including acetylation. Acetylation of lysine residues have traditionally been studied as epigenetic modifiers of histone tails within chromatin that provides an important mechanism for regulating gene expression. In the ...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-06 | PXD008385 | Pride
Mouse Heart Cardiovascular disease Acetylation 
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
TranscriptomicsTranscriptional analysis of the temporal host response to skin infection with the ectoparasitic mite Psoroptes ovis
Transcriptional analysis of ovine skin response to infection with the parasitic mite Psoroptes ovis using the Agilent ovine transcriptome microarray platform. The results of statistical analysis (differential gene expression across the time course of infection was determined using a one way-analysis...
ORGANISM(S): Ovis aries 
2010-08-01 | E-TABM-1012 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of BEAF-32A and BEAF-32B in Drosophila embryos
ChIP-chip analysis of BEAF binding sites in Drosophila embryos using three antibodies: one that recognize both BEAF-32A and BEAF-32B, one specific for BEAF-32A and one specific for BEAF-32B
ORGANISM(S): Drosophila melanogaster 
2009-06-26 | E-TABM-597 | biostudies-arrayexpress
MetabolomicsHigh-Precision Automated Workflow for Urinary Untargeted Metabolomic Epidemiology
Urine is a non-invasive biofluid that is rich in polar metabolites and well-suited for metabolomic epidemiology. However, due to individual variability in health and hydration status, the physiological concentration of urine can differ >15-fold, which can pose major challenges in untargeted LC-MS me...
2021-06-10 | MTBLS2295 | MetaboLights
TranscriptomicsNASH
Non-alcoholic fatty liver disease (NAFLD) is characterized by a series of pathological changes that can progress from simple fatty liver disease to non-alcoholic steatohepatitis (NASH). The objective of this study is to describe changes in global gene expression associated with the progression of NA...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-MEXP-3291 | biostudies-arrayexpress
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