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TranscriptomicsWhole heart transcriptional response to complete and epiblast-specfic deletion of Zic3 in 15.5 dpc mouse embryos
In order to better understand the molecular basis for the heart defects seen in Zic3 null and epiblast CKO embryos, we investigated whether complete or epiblast-specific deletion of Zic3 would impact later embryonic heart development at the transcriptional level by whole genome expression microarray...
ORGANISM(S): Mus musculus 
2012-12-12 | E-GEOD-41674 | biostudies-arrayexpress
UnknownContinued Excellent Outcomes in Previously Untreated Patients With Follicular Lymphoma After Treatment With CHOP Plus Rituximab or CHOP Plus 131I-Tositumomab: Long-Term Follow-Up of Phase III Randomized Study SWOG-S0016.
Not available
S-EPMC6553811 | biostudies-literature
UnknownUS Intergroup Trial of Response-Adapted Therapy for Stage III to IV Hodgkin Lymphoma Using Early Interim Fluorodeoxyglucose-Positron Emission Tomography Imaging: Southwest Oncology Group S0816.
Not available
S-EPMC4966513 | biostudies-literature
ProteomicsCaMKK2 Inactivation by cAMP-PKA Signaling and 14-3-3 Adaptor Proteins
The calcium-calmodulin (Ca2+-CaM) dependent protein kinase kinase-2 (CaMKK2) is activated by increases in intracellular Ca2+ and is a key regulator of cellular and wholebody energy metabolism. CaMKK2 inhibition protects against prostate cancer, hepatocellular carcinoma and metabolic derangements ind...
ORGANISM(S): Homo sapiens (Human) 
2020-11-06 | PXD020133 | Pride
Cyclic amp (camp) Calcium-calmodulin (ca2+-cam) dependent protein kinase kinase-2 (camkk2) Protein kinase a (pka) 14-3-3 adaptor proteins 
ProteomicsProteomic characterization of microdissected epithelium, tumor cells, and stroma from breast tissues
Tissue of the breast is heterogeneous, consisting of a variety of cell types and connective tissue. This heterogeneity is also present in breast tumors and will complicate proteomic analysis, as it is not always clear whether a signal originates from the stromal environment, from normal epithelial o...
ORGANISM(S): Homo sapiens (Human) 
2017-01-11 | PXD003632 | Pride
Proteomics Microdissection Mass spectrometry Breast cancer Tumor microenvironment 
TranscriptomicsExpression profiling of 275 lung cancer specimens
From ~1,700 non-small cell lung cancer specimens collected at the MD Anderson Cancer Center over the years 1997 to 2005, we selected 914 tumors with detailed clinical and pathological information. We extracted RNA and DNA from frozen tissues using histology quality control from 700 cases. RNA was ex...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-41271 | biostudies-arrayexpress
ProteomicsNanodiscs-based proteomics to identify lipid-interacting proteins in yeast
Many soluble proteins interact with membranes to perform important biological functions, including signal transduction, regulation, transport, trafficking and biogenesis. Despite their importance, these protein-membrane interactions are difficult to characterize due to their often-transient nature a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-12-30 | PXD027992 | Pride
Hsp40 Caj1 Silac labeling Nanodiscs Rab gtpase 
TranscriptomicsThe Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3 Hormone [RNA-seq]
Osteocytes are derived from osteoblast lineage cells that become progressively embedded in mineralized bone. Development of the osteocytogenic cell line IDG-SW3 has enabled a temporal and mechanistic investigation of this process. Through RNA-seq analyses, we show that while substantial changes in...
ORGANISM(S): Mus musculus 
2014-05-30 | E-GEOD-54783 | biostudies-arrayexpress
GenomicsThe Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3 Hormone [ChIP-seq]
Osteocytes are derived from osteoblast lineage cells that become progressively embedded in mineralized bone. Development of the osteocytogenic cell line IDG-SW3 has enabled a temporal and mechanistic investigation of this process. Through RNA-seq analyses, we show that while substantial changes in...
ORGANISM(S): Mus musculus 
2014-05-30 | E-GEOD-54782 | biostudies-arrayexpress
TranscriptomicsThe Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3 Hormone
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-05-30 | E-GEOD-54784 | biostudies-arrayexpress
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