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Membrane proteins can be examined in near-native lipid-bilayer environments with the advent of polymer-encapsulated nanodiscs. These nanodiscs self-assemble directly from cellular membranes, allowing in vitro probing of membrane proteins with techniques that had previously been restricted to soluble...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD030958 | Pride
Many soluble proteins interact with membranes to perform important biological functions, including signal transduction, regulation, transport, trafficking and biogenesis. Despite their importance, these protein-membrane interactions are difficult to characterize due to their often-transient nature a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-12-30 | PXD027992 | Pride
FPOP data examining solvent exposure of daptomycin at different concentrations in the presence of nanodiscs with different lipids
ORGANISM(S): Bacteria (ncbitaxon:2) 
2022-11-01 | MSV000090629 | MassIVE
Nanodiscs are emerging as promising nanomaterials for localized therapies as they enable magnetic targeting and near-infrared (NIR) laser–driven photothermal stimulation. In this study, we performed comprehensive proteomic analyses of both tissue and serum from mouse models to elucidate the effects ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-15 | PXD068909 | Pride
Native MS data examining incorporation of daptomycin into intact nanodiscs at different concentrations and with different lipids
ORGANISM(S): Bacteria 
2022-11-16 | MSV000090729 | GNPS
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