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The goal of this study was to define the gene expression changes that take place in the white adipose tissue of KSR2-/- mice at 6 months of age. Three wild type mice and three KSR2-/- mice were used for total RNA extraction from white adipose tissue. The RNA from each mouse was analyzed on one Affy...
ORGANISM(S): Mus musculus 
Onchocerca volvulus, the causative agent of onchocerciasis, infects over 20 million people and can cause severe dermatitis and ocular conditions including blindness. Current mass drug administration treatments do not kill female O. volvulus worms, and common diagnostic tests cannot reliably assess t...
ORGANISM(S): Homo Sapiens Onchocerca Volvulus 
2022-11-22 | PXD033659 |
Extracellular vesicles (EVs) have a great potential in clinical applications, however their isolation from different body fluids and their characterisation are not yet optimal or standardised. Here we report the results of examining the performance of ultrafiltration combined with size exclusion chr...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD009709 | Pride
FocA belongs to the widespread, evolutionarily ancient formate-nitrite transporter 30 (FNT) family of pentameric anion channels and translocates formic acid bidirectionally. 31 Here, we identify compartmentalized polarity distribution across the complete FocA 32 pore structure – resolved at 2.56 Å –...
ORGANISM(S): Escherichia coli 
2025-11-10 | PXD054538 | Pride
It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have been positively selected during human evolution due to effects on aspects of speech and language. Here, we introduce these substitutions into the endogenous Foxp2 gene.of mice. Although these mice are gener...
ORGANISM(S): Mus musculus 
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