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ProteomicsProteomic analysis of laser capture microdissected focal lesions in a rat model of progenitor marker-positive hepatocellular carcinoma
We have shown previously that rapamycin, the canonical inhibitor of the mechanistic target of rapamycin (mTOR) complex 1, markedly inhibits the growth of focal lesions in the resistant hepatocyte (Solt-Farber) model of hepatocellular carcinoma (HCC) in the rat. In the present study, we characterized...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-26 | PXD005845 | Pride
Proteomics Liver Hepatocellular carcinoma Laser capture microscopy Pre-neoplasia 
UnknownDurvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma: A Phase 2 Randomized Clinical Trial.
Not available
S-EPMC6647002 | biostudies-literature
ProteomicsAngiogenic patterning by STEEL, an endothelial-enriched long noncoding RNAAngiogenic patterning by STEEL, an endothelial-enriched long noncoding RNA
Endothelial cell (EC)-enriched protein coding genes, such as endothelial nitric oxide synthase (eNOS), define quintessential EC-specific physiologic functions. It is not clear whether long noncoding RNAs (lncRNAs) also define cardiovascular cell-type specific phenotypes, especially in the vascular e...
ORGANISM(S): Homo sapiens (Human) 
2018-02-28 | PXD008581 | Pride
Endothelium Gene regulations Long noncoding rna 
UnknownResults of the NRG Oncology/RTOG 0848 Adjuvant Chemotherapy Question-Erlotinib+Gemcitabine for Resected Cancer of the Pancreatic Head: A Phase II Randomized Clinical Trial.
Not available
S-EPMC7280743 | biostudies-literature
ProteomicsA cross-disease human microglial framework identifies disease-enriched subsets and tool compounds for microglial polarization.
a. Human microglia play a pivotal role in neurological diseases, but few targeted therapies that directly modulate microglial state or function exist due to an incomplete understanding of microglial heterogeneity. We use single-cell RNA sequencing to profile live human microglia from autopsies or su...
ORGANISM(S): Homo sapiens (Human) 
2025-05-19 | PXD033844 | Pride
A. microglia  single-cell rna sequencing  neurodegeneration  neuroinflammation  disease-associated microglia  alzheimer’s  rnascope-immunofluorescence  microglial model systems  drug targets in neurodegeneration  camptothecin  diapasef  timstofpro 
TranscriptomicsTranscription profiling by array of Rhizobium leguminosarum biovar viciae strain Rlv3841grown on a variety of compounds suspected of being in the rhizosphere compared to cells grown on pyruvate NH4 or glucose NH4
Rhizobium leguminosarum biovar viciae strain Rlv3841 was grown on a variety of compounds suspected of being in the rhizosphere and gene induction was compared to cells grown on either pyruvate NH4 or glucose NH4.
ORGANISM(S): Rhizobium leguminosarum 
2010-08-05 | E-MEXP-2857 | biostudies-arrayexpress
ProteomicsThe Expanding Landscape of Human Protein Phosphorylation C4PR_LIV
Investigation of protein phosphorylation in humans has largely focussed on serine (Ser), threonine (Thr) and tyrosine (Tyr), with proven roles for these modifications in all aspects of life. However, mounting evidence suggests that phosphorylation of non-canonical amino acids, including histidine an...
ORGANISM(S): Homo sapiens (Human) 
2020-06-16 | PXD012188 | Pride
Strong anion exchange Phosphoaspartate Non-canonical phosphorylation Phosphoproteomics Mass spectrometry 
TranscriptomicsPtp107 versus wild type Rlv3841
Strain PtsP107 has a Tn5 insertion in PtsP and it was grown on glucose/ ammonia minimal medium and gene expression compared to the wild type Rhizobium leguminosarum biovar viciae strain Rlv3841 grown on the same medium.
ORGANISM(S): Rhizobium leguminosarum 
2011-09-23 | E-MEXP-3381 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Rhizobium leguminosarum biovar viciae strain RU2386 grown overnight in glucose aspartate minimial medium and next day resuspended in glucose glutamate
Rhizobium leguminosarum biovar viciae strain RU2386 was grown overnight on glc asp and the next day it was resuspended in glucose glutamate. Gene expression before resuspension was compared to the 2 h resuspended sample.
ORGANISM(S): Rhizobium leguminosarum 
2010-10-03 | E-MEXP-2901 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Rhizobium leguminosarum biovar viciae strain Rlv3841inculated at either 10-3 or 10-8 CFU into the rhizosphere of peas
Rhizobium leguminosaeum biovar viciae strain Rlv3841 was inoculated at either 10_3 CFU ot 10_8 CFU into the rhizosphere of 7 d old peas and the bacteria were harvested 7 days post inoculation. They were compared indircetly against a control of glucose ammonia grown laboratory cells.
ORGANISM(S): Rhizobium leguminosarum 
2010-08-04 | E-MEXP-2854 | biostudies-arrayexpress
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