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Identification of in vivo binding targets of Met4 and Met32 by conducting chromatin immunoprecipitation studies using genomic tiling arrays (ChIP-on-chip 4X44K whole yeast genome arrays by Agilent) following 90 minutes Met4 hyperactivation.
ORGANISM(S): Saccharomyces cerevisiae 
Hypoxia-inducible factor 1 (HIF-1) activates the transcription of genes encoding proteins that enable cells to adapt to reduced O2 availability. HIF-1 target genes play a central role in mediating physiological processes that are dysregulated in cancer and heart disease, including angiogenesis, e...
ORGANISM(S): Homo sapiens (Human) 
2016-06-06 | PXD003792 | Pride
hBM-MSC were expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability;µA analysis were performed p2/p5 (n=10)and p5/p10 (n=5) to examine if the genetic background of hBM-MSC is changeing during their high-grade expansion;
ORGANISM(S): Homo sapiens 
hBM-MSC were expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability;µA analysis were performed p2/p5 (n=10)and p5/p10 (n=5) to examine if the genetic background of hBM-MSC is changeing during their high-grade expansion;
ORGANISM(S): Homo sapiens 
Experiments were designed to compare white adipose tissue (WAT) or brown adipose tissue (BAT) -in male and female mice- between Bscl2 knock-out mice and their wild-type control mice. RNA was pooled to obtain 2x 8µg per tissue source and subjected to dye-swap hybridization.
ORGANISM(S): Mus musculus 
Gene expression profiling in 5 tissues (WAT, BAT, CM, LIV, SM) from HSL-/- mice versus wildtype (HSL+/+) mice.
ORGANISM(S): Mus musculus 
This experiment was designed to identify C/ebp alpha target genes during the process of adipogenesis by means of comparison of differentiating (wild-type) cells to a perturbation model (transgenic cells). For this, gene expression profiling during adipogenesis of mouse embryonic fibroblasts (MEFs) ...
ORGANISM(S): Mus musculus 
Gene expression profiling in 6 tissues (white adipose tissue (WAT), brown adipose tissue (BAT), cardiac muscle (CM), liver (LIV), kidney (KID), skeletal muscle (SM)) from ATGL(-/-) mice versus wildtype (ATGL+/+) mice.
ORGANISM(S): Mus musculus 
The aim of the project is to identify the late (24h) host response related to Gram positive (S. pyogenes) or Gram negative (E. coli) induced sepsis in a controlled sepsis model 24 hours a. Therefore a well defined baboon sepsis model, established at the Ludwig Boltzmann Institute for experimental an...
ORGANISM(S): Papio hamadryas 
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