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ProteomicsFkbp5 Gene Deletion: Impacts on Circadian Rhythmicity and Brain Proteomics in Aged Mice
FKBP51, also known as FK506-binding protein 51, is a molecular chaperone and scaffolding protein with significant roles in regulating hormone signaling and stress responding. Genetic variants in FKBP5, which encodes FKBP51, have been implicated in a growing number of neuropsychiatric disorders, whic...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-05 | PXD049439 | Pride
Knock out Brain Hippocampus Dia Ko Prm Aged Amygdala Mouse Fkbp5 
TranscriptomicsFKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance.
Glucocorticoid excess is linked to central obesity, adipose tissue insulin resistance and type 2 diabetes mellitus. The aim of our study was to investigate the effects of dexamethasone on gene expression in human subcutaneous and omental adipose tissue, in order to identify potential novel mechanism...
ORGANISM(S): Homo sapiens 
2014-08-18 | E-GEOD-42902 | biostudies-arrayexpress
GenomicsCorticosteroid-induced chromatin loop dynamics at the FKBP5 gene
Corticosteroid-induced chromatin loop dynamics at the FKBP5 gene
PRJNA560981 | ENA
GenomicsTranscriptomic analysis for understanding differential gene expression upon FKBP5 knockdown
Transcriptomic analysis for understanding differential gene expression upon FKBP5 knockdown
PRJNA716642 | ENA
GenomicsInhibiting FKBP5 might alleviate obstetric antiphospholipid syndrome by regulating macrophage polarization.
Inhibiting FKBP5 might alleviate obstetric antiphospholipid syndrome by regulating macrophage polarization.
PRJNA1195595 | ENA
OtherCorticosteroid-induced chromatin loop dynamics at the FKBP5 gene
FKBP5 is a long glucocorticoid-inducible gene implicated in psychiatric disorders. To investigate the complexities of chromatin interaction frequencies at the FKBP5 topologically associated domain (TAD), we deployed fifteen one-to-all chromatin capture viewpoints near gene promoters, enhancers, intr...
ORGANISM(S): Homo sapiens 
2023-10-15 | GSE136034 | GEO
GenomicsSevoflurane increases FKBP5 expression in microglia in the brains of aged marmosets and mice
Sevoflurane increases FKBP5 expression in microglia in the brains of aged marmosets and mice
PRJNA981536 | ENA
GenomicsAstrocytic FKBP5 regulates neuroinflammation and cognitive outcomes in male mouse models of excitotoxic epilepsy
Astrocytic FKBP5 regulates neuroinflammation and cognitive outcomes in male mouse models of excitotoxic epilepsy
PRJNA1244893 | ENA
UnknownMethylation of the FKBP5 gene in association with FKBP5 genotypes, childhood maltreatment and depression.
Not available
S-EPMC6461917 | biostudies-literature
TranscriptomicsInhibiting FKBP5 might alleviate obstetric antiphospholipid syndrome by regulating macrophage polarization.
The disturbance of immune balance at the maternal-fetal interface is a significant contributor to obstetric antiphospholipid syndrome (OAPS); however, the precise mechanisms underlying this disturbance remain unclear. This study investigates the immune regulatory role of FK506-binding protein 5 (FKB...
ORGANISM(S): Homo sapiens 
2025-04-07 | GSE283798 | GEO
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