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MetabolomicsMetabolomics reveals an involvement of pantothenate for male production responding to the short-day stimulus in the water flea, Daphnia pulex
Under favorable conditions, the micro-crustacean Daphnia pulex produces female offspring by parthenogenesis, whereas in response to various unfavorable external cues, they produce male offspring to induce sexual reproduction (environmental sex determination: ESD). We recently established a suitable ...
2017-04-03 | MTBLS259 | MetaboLights
TranscriptomicsPreadaptation of Yersinia pestis to resist mammalian innate immunity during transit through the flea vector
Yersinia pestis, the agent of plague, is transmitted to mammals by infected fleas. Y. pestis exhibits a distinct life stage in the flea, where it grows in the form of a cohesive biofilm that promotes transmission. After transmission, the temperature shift to 37°C induces many known virulence factors...
ORGANISM(S): Yersinia pestis 
2010-04-06 | E-GEOD-16493 | biostudies-arrayexpress
ProteomicsA substrate-like thrombin inhibitor from the saliva of the flea Xenopsylla cheopis is resistant to cleavage by the enzyme
XC-43 is a small peptide identified in the sialome of the flea Xenopsylla cheopis and act as a fast, tight-binding inhibitor of thrombin with a dissociation constant of less than 10 pM. The crystal structure of XC-43 in complex with thrombin shows that despite its substrate-like binding mode, XC-43 ...
ORGANISM(S): Xenopsylla cheopis 
2022-02-16 | PXD028851 | Pride
Flea Blood feeding X-ray crystallography Thrombin 
ProteomicsRole of the Yersinia pestis Phospholipase D (Ymt) in the Initial Aggregation Step of Biofilm Formation in the Flea
Transmission of Yersinia pestis by fleas depends on the formation of condensed bacterial aggregates embedded within a gel-like matrix that localize to the proventricular valve in the flea foregut and interfere with normal blood feeding.The matrix of the bacterial aggregates is complex,containing lar...
ORGANISM(S): Mus musculus (Mouse) Xenopsylla cheopis Yersinia pestis CO92 
2024-05-06 | PXD046759 | Pride
Flea Biofilm Yersinia pestis 
TranscriptomicsStressor mRNA expression profiling of three different stressors in the water flea Daphnia magna
Microarray analyses were used to evaluate patterns of gene transcription following exposure of the waterflea Daphnia magna to two natural and one anthropogenic stressor. cDNA microarrays compiled of three life stage specific and three stressor-specific EST libraries, yielding 1734 different EST sequ...
ORGANISM(S): Daphnia magna 
2013-09-01 | E-GEOD-24322 | biostudies-arrayexpress
TranscriptomicsPreadaptation of Yersinia pestis to resist mammalian innate immunity during transit through the flea vector
Yersinia pestis, the agent of plague, is transmitted to mammals by infected fleas. Y. pestis exhibits a distinct life stage in the flea, where it grows in the form of a cohesive biofilm that promotes transmission. After transmission, the temperature shift to 37°C induces many known virulence factors...
ORGANISM(S): Coxiella burnetii Chlamydia trachomatis Streptococcus pyogenes Borreliella burgdorferi Staphylococcus aureus Yersinia pestis 
2010-04-06 | GSE16493 | GEO
TranscriptomicsDifferential gene expression patterns of Yersinia pestis and Yersinia pseudotuberculosis during infection and biofilm formation in the flea digestive tract
Yersinia pestis, the etiologic agent of plague, emerged as a flea-borne pathogen only within the last 6,000 years. Just five simple genetic changes in the Yersinia pseudotuberculosis progenitor, which served to eliminate toxicity to fleas and to enhance survival and biofilm formation in the flea dig...
ORGANISM(S): Yersinia pestis Yersinia pseudotuberculosis Yersinia pestis KIM10+ Yersinia pestis CO92 
2019-01-28 | GSE119243 | GEO
TranscriptomicsRole of the PhoP-PhoQ Gene Regulatory System in Adaptation of Yersinia pestis to Environmental Stress in the Flea Digestive Tract
The Yersinia pestis PhoPQ gene regulatory system is induced during infection of the flea digestive tract and is required to produce adherent biofilm in the foregut, which greatly enhances bacterial transmission during a flea bite. To understand the in vivo context of PhoPQ induction and to determine...
ORGANISM(S): Yersinia pestis Borreliella burgdorferi Staphylococcus aureus Coxiella burnetii Chlamydia trachomatis Streptococcus pyogenes 
2017-02-09 | GSE61558 | GEO
UnknownPredictors for abundance of host flea and floor flea in households of villages with endemic commensal rodent plague, Yunnan Province, China.
Not available
S-EPMC3066137 | biostudies-literature
GenomicsACT flea iflavirus
Complete genome sequence analysis of plant growth-promoting bacterium, Isoptericola sp. AK164 isolated from the rhizosphere of Avicennia marina growing at the Red Sea coast
PRJDB15678 | ENA
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