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ProteomicsPhoto-crosslinking of SurA (p-azido-Phe) to unfolded Omps (OmpA and OmpX)
To investigate the structural basis of SurA’s chaperone function, we characterized crosslinks between it and two of its clients, OmpA and OmpX, and used those as distance restraints to build structural models.
ORGANISM(S): Escherichia coli 
2020-10-29 | PXD021870 | Pride
Periplasm Chaperones Protein biogenesis 
ProteomicsChemical-crosslinking of SurA with DSBU to unfolded Omps (OmpA and OmpX)
To investigate the structural basis of SurA’s chaperone function, we characterized crosslinks between it and two of its clients, OmpA and OmpX, and used those as distance restraints to build structural models.
ORGANISM(S): Escherichia coli 
2020-10-29 | PXD021872 | Pride
Periplasm Chaperones Protein biogenesis 
ProteomicsA Proteome-Wide Map of Chaperone-Assisted Protein Refolding in a Cytosol-like Milieu
The journey by which proteins navigate their energy landscapes to their native structures is complex, involving (and sometimes requiring) many cellular factors and processes operating in partnership with a given polypeptide chain’s intrinsic energy landscape. The cytosolic environment and its compl...
ORGANISM(S): Escherichia coli 
2022-11-23 | PXD030869 | Pride
Protein refolding Chaperone refolding Groel/es folding Proteomics 
UnknownConditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity.
Not available
S-EPMC6954370 | biostudies-literature
GenomicsGlioma GWAS summary statistics
Meta-analysis association statistics from case-control analysis (includes imputed SNPs)
EGAD00010001657 | EGA
GenomicsSummary statistics from genome-wide association study in glioma of 12,488 cases and 18,169 controls.
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, but individual studies have had limited power to identify risk loci. We performed a meta-analysis of existing GWAS and two new GWAS, which totaled 12,488 cases and 18,169 controls. We identified five ...
EGAS00001003372 | EGA
GenomicsGlioma GWAS summary statistics DAC
Data Access Committee EGAC00001001116
EGAC00001001116 | EGA
GenomicsCohort-Based Genome-Wide Association Study of Glioma (GliomaScan)

We conducted a new independent GWAS of adult glioma using 1,856 cases and 4,955 controls from 14 cohort studies belonging to the Cohort Consortium, 3 case-control studies, and 1 population-based case only study. Cases were newly diagnosed glioma [ICDO-3 codes 9380-9480 or equivalent], and control...

phs000652.v1.p1 | EGA
UnknownTherapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.
Not available
S-EPMC5310766 | biostudies-literature
UnknownEffectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial.
Not available
S-EPMC10698555 | biostudies-literature
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