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ModelsMullinax2016 - Mathematical model of tumor-immune cell interactions to optimize the meta-phenotype of TIL subpopulations
This model is described in the publication: John Mullinax, Cliona O’Farrelly, Jacob G. Scott, Andreas Buttenschön, Asmaa E. Elkenawi, Fadoua El Moustaid, Alexander G. Fletcher, Clemens Grassberger, Eunjung Kim, Andriy Marusyk, Harry L.O. McClelland, Daria Miroshnychenko, Daniel Nichol. "Harnessing t...
2021-09-11 | MODEL2109110006 | BioModels
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Spleen gene expression in uninfected, resolved and chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36544 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36533 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in tumor and non-tumor samples from chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36545 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Kidney gene expression in uninfected, resolved and chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36541 | biostudies-arrayexpress
TranscriptomicsSustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B
Background & Aims: New therapies for chronic hepatitis B (CHB) are urgently needed since current treatments rarely lead to cure. We evaluated whether the oral small molecule toll-like receptor (TLR7) agonist GS-9620 could induce durable anti-viral efficacy in woodchucks chronically infected with woo...
ORGANISM(S): Marmota monax 
2015-04-16 | E-GEOD-67935 | biostudies-arrayexpress
TranscriptomicsMechanisms of adaptation to stress and control of virulence in Pseudomonas aeruginosa: the OxyR regulons
Oxidative stress caused by exposure to reactive oxygen species (ROS), is a major challenge for aerobic and especially anaerobic organisms. Bacteria coordinate the response to oxidative stress through the LysR-type transcriptional regulator (LTTR) OxyR. Extensive studies have focused on the classical...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2013-12-13 | E-GEOD-33871 | biostudies-arrayexpress
UnknownSex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females.
Not available
S-EPMC10994548 | biostudies-literature
TranscriptomicsTargeting the novel SALL4/CBL-B pathway by HDAC inhibitor MS-275 in lung cancer
The overall survival of lung cancer patients remains dismal despite the availability of targeted therapies. Oncofetal protein SALL4 is a novel cancer target. We herein report that SALL4 was aberrantly expressed in a subset of lung cancer patients with poor survival. SALL4 silencing by RNA interferen...
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-68959 | biostudies-arrayexpress
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
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