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MetabolomicsMulti-omics Insights into Postnatal Skeletal Muscle Development in Duroc Pigs

Skeletal muscles, accounting for 40% of mammalian body mass, exhibit pronounced heterogeneity due to distinct anatomical locations. Animal husbandry excessively focuses on longissimus dorsi (LDM) development, while neglecting other muscles. In this study, we integrated Bulk RNA Sequencing (bulk R...

2025-09-09 | MTBLS12963 | MetaboLights
MetabolomicsDelayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

Exercise is fundamental to healthy aging, yet the degree to which it mitigates age-related molecular changes and how varying physical fitness levels influence the molecular response to exercise with age remain unclear. To address this, we performed transcriptomics, lipidomics, and metabolomics on...

2026-04-09 | MTBLS12824 | MetaboLights
TranscriptomicsThe RNA binding protein Arrest (Aret) regulates myofibril maturation in Drosophila flight muscle
In Drosophila, fibrillar flight muscles (IFMs) enable flight, while tubular muscles mediate other body movements. Here, we use RNA-sequencing and isoform-specific reporters to show that spalt major (salm) determines fibrillar muscle physiology by regulating transcription and alternative splicing of ...
ORGANISM(S): Drosophila melanogaster 
2014-12-23 | E-GEOD-63707 | biostudies-arrayexpress
GenomicsThe Hox protein Antennapedia orchestrates Drosophila adult flight muscle development
The Hox protein Antennapedia orchestrates Drosophila adult flight muscle development
PRJNA1117832 | ENA
GenomicsFrom Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines
From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines
PRJNA1292191 | ENA
GenomicsGain of function of Antp in developing flight muscle prevents determination of the fibriallar muscle fate
Gain of function of Antp in developing flight muscle prevents determination of the fibriallar muscle fate
PRJNA1117839 | ENA
TranscriptomicsMicroarray (one-color) gene expression analysis of Euglena gracilis subjected to altered acceleration during parabolic flight
Euglena gracilis is a unicellular freshwater flagellate, which uses the gravitational vector for orientation in the water column in the dark. This allows the cell to reach areas in the water column for reproduction and growth. How exactly the gravitational vector is perceived, and which intracellula...
ORGANISM(S): Euglena gracilis 
2019-07-09 | E-MTAB-8064 | biostudies-arrayexpress
GenomicsIn-Flight Human Skeletal Muscle Tissue Chip Autonomous Payload: Validation of Fiber Type and Metabolic Changes Due to Space Flight
In-Flight Human Skeletal Muscle Tissue Chip Autonomous Payload: Validation of Fiber Type and Metabolic Changes Due to Space Flight
PRJNA981485 | ENA
ProteomicsBruno 1 regulates cytoskeleton dynamics and a temporal splicing transition to promote myofibril assembly, growth and maturation in Drosophila flight muscle
Muscles undergo developmental transitions in gene expression and alternative splicing that are necessary to refine sarcomere structure and contractility. CUG-BP and ETR-3-like (CELF) family RNA binding proteins are important regulators of RNA processing during myogenesis that are misregulated in dis...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-03-08 | PXD043308 | Pride
Muscle development Drosophila Flight muscle Celf Bruno 1 
GenomicsCharacterisation of TET function during indirect flight muscle development
Characterisation of TET function during indirect flight muscle development
PRJNA1182650 | ENA
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