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ProteomicsSpxA1 and SpxA2 Function as a Stoichiometry-Dependent Regulatory Rheostat Governing Virulence Gene Expression in Group A Streptococcus — DIA Proteomics
Group A Streptococcus (GAS) encodes two paralogs of the Spx transcriptional regulator, SpxA1 and SpxA2, which interact with RNA polymerase to modulate virulence gene expression. SpxA2 is directly regulated by the LiaFSR three-component system in response to antimicrobial peptide stress. To define ho...
ORGANISM(S): Streptococcus pyogenes MGAS315 
2026-07-13 | PXD079489 | Pride
Spx Group a streptococcus Covr 
GenomicsCytokine-mediated differentiation reflects genome-wide loss of a uSTAT transcriptional program
uSTAT transcriptional program HPC7 cells were fixed with either 1% formaldehyde for 10 mins. Chromatin was isolated, sonicated for 7 mins (30 sec on, 30 sec off), and specific antibodies were used to pull down the transcription factors of insterest after a pre-clearing step. Chromatin was washed, de...
ORGANISM(S): Mus musculus 
2016-01-05 | E-GEOD-70697 | biostudies-arrayexpress
UnknownSARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
Not available
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UnknownSocializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats.
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UnknownLiraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
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S-EPMC10208981 | biostudies-literature
UnknownClinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.
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UnknownRisk of COVID-19 after natural infection or vaccination.
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S-EPMC10518569 | biostudies-literature
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
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