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TranscriptomicsExpression and CGH array profiling of ductal carcinoma (135 tumor samples)
A Cartes d'Identité des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 46 samples| Agilent SurePrint G3 Human CGH Microarray 4x180K Arrays : 135 samples| To explore the prognostic value of genomic alterations pr...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-MTAB-748 | biostudies-arrayexpress
TranscriptomicsCGH array analysis of pituitary tumors
CGH array analysis was performed on 195 fresh-frozen pituitary tumors (56 gonadotroph, 11 null-cell, 56 somatotroph, 39 lactotroph and 33 corticotroph), with 5 years post-surgery follow-up
ORGANISM(S): Homo sapiens 
2021-01-01 | E-MTAB-9237 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ductal and lobular breast cancers with familial or Cowden disease history.
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | 74 samples on Affymetrix HG-U133 Plus 2.0 GeneChips arrays for 74 patients. 5 samples on CGH CIT v7 | Breast carcinoma is the main malignant tumor occurring in patients wit...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-TABM-854 | biostudies-arrayexpress
UnknownRuvAB is essential for replication forks reversal in certain replication mutants.
Not available
S-EPMC1383526 | biostudies-literature
TranscriptomicsNF1 microdeletions characterization by custom high-resolution array CGH
To allow accute charaterization of NF1 locus constitutional microdeletion in 70 NF1 patients, a custom array CGH was developped. Goal was to obtain genomic rearrangements fine characterization in order to perform genotype-phenotype correlation in NF1 microdeleted patients. To serve as a reference g...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-19730 | biostudies-arrayexpress
TranscriptomicsTen percent of aberrant cells is sufficient for detection of DNA copy number alterations (part 3)
Array Comparative Genomic Hybridization (aCGH) is a widely used technique to assess chromosomal copy number alterations. Chromosomal content, however, is often not uniform throughout cell populations. The aim of our present study is to evaluate to what extent aCGH can detect DNA copy number alterat...
ORGANISM(S): Homo sapiens 
2012-10-21 | E-GEOD-36989 | biostudies-arrayexpress
TranscriptomicsIGR_PhilippeVielh_THY_CGH
Although fine needle aspiration (FNA) cytology is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains challenging in follicular neoplasms. Identification of genomic alterations in cytological specimens that distinguish between benign and malignant follicu...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-MTAB-1575 | biostudies-arrayexpress
TranscriptomicsTen percent of aberrant cells is sufficient for detection of DNA copy number alterations (part 1)
Array Comparative Genomic Hybridization (aCGH) is a widely used technique to assess chromosomal copy number alterations. Chromosomal content, however, is often not uniform throughout cell populations. The aim of our present study is to evaluate to what extent aCGH can detect DNA copy number alterat...
ORGANISM(S): Homo sapiens 
2012-10-21 | E-GEOD-36856 | biostudies-arrayexpress
UnknownClostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL.
Not available
S-EPMC6867657 | biostudies-literature
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant [Comparative Genomic Hybridization (DNA) profiling]
Drug resistance is a major public health challenge in Leishmaniasis chemotherapy, particularly in the case of emerging Leishmania/HIV-1 co-infections. Recently, we have delineated the mechanism of cell death induced by the HIV-1 protease inhibitor, Nelfinavir, in the Leishmania parasite. In order to...
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42195 | biostudies-arrayexpress
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