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Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
Salivary gland sporozoites of the malaria parasite Plasmodium express a major surface coat protein, CSP. The N-terminus of this protein is hypothesized to be enzymatically processed, revealing a Gln residue which is then enzymatically converted pyro-Glu. We analyzed P. falciparum salivary gland spor...
ORGANISM(S): Plasmodium falciparum NF54 
2025-05-07 | PXD052186 | Pride
We compared transcript levels at several points along the asexual blood cycle between 21 P. falciparum lines. These 21 parasite lines are organized in 4 sets of parasite lines, with all parasite lines within a set sharing a clonal origin. We compared transcript levels within each set. We also perfor...
ORGANISM(S): Plasmodium falciparum 
To ascertain genomic alterations associated with Imatinib resistance in chronic myeloid leukaemia, we performed high resolution genomic analysis of CD34+ cells from 25 Imatinib (IM) resistant and 11 responders CML patients. Using patients' T-cells as reference, we found significant association betwe...
ORGANISM(S): Homo sapiens 
373 tumors were profiled for copy-number alterations with the high-resolution Agilent 244A aCGH Array. Tumor samples were assayed on Agilent Human Genome CGH 244A Microarrays with the intent of surveying the landscape of genomic alterations in 5 tumor types. Human male genomic DNA (Promega P/N G1471...
ORGANISM(S): Homo sapiens 
Comparative genomic hybridisations of new cyanphage isolates against an array with probes designed against the core genome of the four cyanophage isolates S-PM2, Syn9, P-SSM2 and P-SSM4
ORGANISM(S): Synechococcus phage S-IO17 
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
To explore chorionic gonadotropin (CG)-regulated gene expression in the primate corpus luteum (CL), adult female rhesus macaques were treated with a model of simulated early pregnancy (SEP). Total RNA was isolated from individual CL and hybridized to AffymetrixM-bM-^DM-" GeneChip Rhesus Macaque Geno...
ORGANISM(S): Macaca mulatta 
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