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 Florfenicol is valued for its clinical safety, particularly its reduced bone marrow toxicity compared to other old antibiotics of chloramphenicols. However, the rise of bacterial resistance threatens its efficacy. To address this, we evolved a florfenicol-resistant strain of Vibrio par...

2025-10-14 | MTBLS13132 | MetaboLights
Here we analyzed the proteomic response of the important Gram-negative fish pathogen A. salmonicida to iron-limitation, the antibiotic florfenicol and an elevated incubation temperature. Proteins of different subcellular fractions (cytosol, inner membrane, outer membrane, extracellular and outer mem...
ORGANISM(S): Aeromonas salmonicida salmonicida 
2022-08-30 | PXD034641 | Pride
iTRAQ-based proteomics was performed to explore the mechanism underlying Florfenicol-induced stem cell toxicity and assess the overall protein changes in P19SCs post FLO treatment.
ORGANISM(S): Mus Musculus 
2021-09-26 | PXD028764 |
Transcriptome sequencing of Paracoccus denitrificans ATCC19367 with florfenicol exporsure
We report the application of transcriptome sequencing technology in florfenicol interfering with denitrification by Paracoccus denitrificans. More than 30 billion bases of sequences were obtained by sequencing analysis. We found 433 differentially expressed genes, of which 292 genes were down-regula...
ORGANISM(S): Paracoccus denitrificans 
2021-04-13 | GSE166910 | GEO
Because antibiotics have been widely used to prevent severe losses due to infectious fishery diseases, the liberal application and overuse of antibiotics has led to the spread and evolution of bacterial resistance, food safety hazards, and environmental issues. The use of some antibiotics, including...
ORGANISM(S): Ctenopharyngodon idella 
The use of some antibiotics, including florfenicol and enrofloxacin, is allowed in aquaculture in China. Accordingly, to better address the concerns and questions associated with the impact of administered enrofloxacin and florfenicol to grass carp, here we investigated the transcriptome of the inte...
ORGANISM(S): Ctenopharyngodon idella 
Anaerobic florfenicol defluorination
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