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TranscriptomicsEssential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency
Here we delineate the roles of RNA binding for WDR5 function on chromatin state and murine embryonic stem cell (ESC) maintenance. Examination of global transcriptional changes and mapping genome-wide transcription factors occupancy at distinct time points during the transdifferentiation process
ORGANISM(S): Mus musculus 
2014-02-12 | E-GEOD-53035 | biostudies-arrayexpress
ProteomicsThe modified RNA base acp3U is an attachment site for N-glycans in glycoRNA
GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell surface. While previous work supported a covalent linkage between RNA and glycans, the direct chemical nature of the RNA-glycan connection was not described. Here we develop a sensitive and scalable protocol t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-31 | MSV000093213 | MassIVE
GenomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20530 | biostudies-arrayexpress
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20529 | biostudies-arrayexpress
UnknownComprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
Not available
S-EPMC3396450 | biostudies-literature
TranscriptomicsTranscriptional profiling of lncRNAs and novel transcribed regions across a diverse panel of archived human cancers
Molecular characterization of tumors has been critical for identifying important genes in cancer biology and for improving tumor classification and diagnosis. Long non-coding RNAs (lncRNAs), as a new, relatively unstudied class of transcripts, provide a rich opportunity to identify both functional d...
ORGANISM(S): Homo sapiens 
2012-08-24 | E-GEOD-28866 | biostudies-arrayexpress
UnknownInnate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.
Not available
S-EPMC11382880 | biostudies-literature
UnknownLapses in Care Among Patients Assigned to Ranibizumab for Proliferative Diabetic Retinopathy: A Post Hoc Analysis of a Randomized Clinical Trial.
Not available
S-EPMC8532036 | biostudies-literature
UnknownISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19.
Not available
S-EPMC9339000 | biostudies-literature
UnknownAspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8598213 | biostudies-literature
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