Focal adhesion kinase

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CHEBI:143106 (1)
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Adenosine (3)
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Lab affiliation

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Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (2)
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Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
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Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom (1)
Centre for Cancer Cell & Molecular Biology Barts Cancer Institute, Queen Mary University of London Charterhouse Square London EC1M 6BQ U.K. (1)
Centre for Craniofacial & Regenerative Biology, King’s College London/ Randall Centre for Cell & Molecular Biophysics, King’s College London (1)
Centre for Genomic Regulation (CRG),Barcelona, Spain (1)
Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ Tel: +44 (0)20 7882 8266 | Fax: +44 (0)20 7882 3891 | Email: p.cutillas@qmul.ac.uk (1)
Centre for Genomics and Computational Biology, Barts Cancer Institute, Queen Mary Universty of London (1)
Centre for Haemato-oncology, Barts Cancer Institute, Queen Mary University of London, London, EC1M6BQ, UK (1)
Chair, Quantitative Proteomics Director, Proteome Center Tuebingen Interfaculty Institute for Cell Biology University of Tuebingen Auf der Morgenstelle 15 72076 Tuebingen Germany (1)
Department of Pediatrics Indiana University School of Medicine Riley Hospital for Children (1)
Department of Science, University of Chieti, Italy (1)
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Division of Immunobiology, Cincinnati Children’s Hospital, Cincinnati, OH Department of Pediatrics, University of Cincinnati, Cincinnati OH Correspondence: (1)
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King Abdullah University of Science and Technology (1)
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Massachusetts Institute of Technology, Department of Biological Engineering, David H Koch Institute for Integrative Cancer Research (1)

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Focal Adhesion Kinase Dependent Expression

The goal of this study was to identify transcripts, which are differentially regulatulated in the presence and absence of Focal Adhesion Kinase. As Focal Adhesion Kinase activity can depend upon cell density (Snijder et al. Nature 2009), biological replicates where cells, were seeded very sparsely o...

ORGANISM(S): Mus musculus

2013-09-17 | E-GEOD-43873 | biostudies-arrayexpress

siRNA profiling if human MCF-7 cell line to investigate the role of FAK, dominant-negative FAK, FAK-CD and FAKsiRNA in MCF-7 human breast cancer cell tumorigenesis

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that plays an important role in proliferation, motility, adhesion, invasion, angiogenesis, and survival signaling. Focal adhesion kinase has been shown to be overexpressed in many types of tumors, including breast cancer at early stages o...

ORGANISM(S): Homo sapiens

2009-08-22 | E-GEOD-11581 | biostudies-arrayexpress

Proteomic analysis of integrin-associated adhesion complexes isolated from cells treated with DMSO or FAK inhibitor

Human foreskin fibroblast cells were spread on fibronectin (FN) for 1 h and treated with DMSO or FAK inhibitor (3 uM, AZ13256675 (termed AZ675 for short)) for 1 h. Integrin-associated adhesion complexes isolated from these cells were analysed by mass spectrometry to determine changes in adhesion com...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-23 | MSV000080089 | MassIVE

Acinar to β-like cell conversion through inhibition of focal adhesion kinase

PRJNA1055555 | ENA

Focal Adhesion Kinase Dependent Expression

ORGANISM(S): Mus musculus

2013-09-17 | GSE43873 | GEO

Effect of norepinephrine and focal adhesion kinase (FAK) knockdown in prostate cancer

PRJNA488279 | ENA

Liver Epithelial Focal Adhesion Kinase Modulates Fibrogenesis and Hedgehog Signaling

PRJNA660335 | ENA

Semaphorin 5A modulates focal adhesion pathway and lamellipodia formation in melanoma

Introduction Metastatic potential and rising incidence make cutaneous melanoma a major health concern worldwide. Although the therapies currently in use have proven effective, their use is limited by side effects arising and development of drug resistance. For this reason, re...

ORGANISM(S): Homo sapiens (Human)

2025-12-01 | PXD065661 | Pride

Semaphorin 5a Melanoma Lamellipodia Focal adhesion

Mus musculus

Focal Adhesion Kinase Dependent Expression

PRJNA187977 | ENA

Structural and mechanistic insights into mechanoactivation of focal adhesion kinase.

Not available

S-EPMC6452671 | biostudies-literature

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