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TranscriptomicsComparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease
To search for biomarkers to differentiate Adult-Onset Steroid Sensitive focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Compared the profiles of glomerular transcriptomes between patients with FSGS and patients with MCD using microarray analysis. This dataset is part of ...
ORGANISM(S): Homo sapiens 
2017-01-04 | E-GEOD-69814 | biostudies-arrayexpress
TranscriptomicsBulk-RNAseq data of podocytes treated with FSGS sera
Human immortalised podocytes were exposed to 10% sera from a patient with focal segmental glomerulosclerosis when they were presenting with disease, on weekly vincristine treatment, and in remission. RNA was extracted with the Qiagen RNEasy plus kit, purity and concentration were assessed by nanodro...
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-14604 | biostudies-arrayexpress
ProteomicsA Circulating Antibody Panel for Pre-transplant Prediction of FSGS Recurrence after Kidney Transplantation
Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation is a cause of early and accelerated graft loss. Immuneadsorption can alleviate renal dysfunction and suggests that circulating antibodies (Ab) are likely implicated in disease pathogenesis. To evaluate pathogenic A...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-57099 | biostudies-arrayexpress
ProteomicsLaser microdissection and mass spectrometry shows loss of podocyte proteins in minimal change disease and focal segmental glomerulosclerosis.
Minimal change disease and primary focal segmental glomerulosclerosis (FSGS) are common causes of nephrotic syndrome. Both diseases present with massive proteinuria and widespread foot process effacement on electron microscopy examination. On the other hand, secondary FSGS can also present with sign...
ORGANISM(S): Homo sapiens (Human) 
2025-12-29 | PXD057165 | Pride
Laser microdissection Focal segmental glomerulosclerosis Mass spectrometry Minimal change disease 
TranscriptomicsGlomerular transcriptome from subjects in the NEPTUNE cohort
Glomerular Transcriptome from subjects in the NEPTUNE cohort. A number of samples profiled in this analysis were also profiled in Series GSE68127, and Series GSE108113. RNA from the glomerular compartment of was extracted and processed for hybridization on Affymetrix microarrays. Contributor: NEPTU...
ORGANISM(S): Homo sapiens 
2018-05-17 | E-GEOD-104066 | biostudies-arrayexpress
ProteomicsPathogenesis of focal segmental glomerulosclerosis and minimal change disease
Podocyte injury is the hallmark of both focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) and is ultimately reflected in foot process effacement proteinuria. Triggers and pathogenic pathways leading to podocyte cytoskeleton rearrangements are however incompletely explained. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-12 | MSV000097297 | MassIVE
GenomicsExon Level Expression Profiling of focal segmental glomerulosclerosis
Exon Level Expression Profiling of focal segmental glomerulosclerosis
PRJNA496420 | ENA
ProteomicsIdiopathic focal segmental glomerulosclerosis plasmas increase lipid droplet formation and perilipin-2 expression in human podocytes
Background: Many patients with idiopathic focal segmental glomerulosclerosis (FSGS) develop recurrence of proteinuria after kidney transplantation. Several circulating permeability factors (CPFs) responsible for recurrence have been suggested, but there is no consensus about the identity of CPFs in ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-22 | PXD028536 | Pride
Circulating permeability factor Podocytes Lipid droplets Perilipin-2 Idiopathic focal segmental glomerulosclerosis (fsgs) 
ProteomicsDysregulated proteases homoeostasis in primary focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) represents a pattern of injuries seen in histopathology rather than a distinct disease. Presently, FSGS is categorized into primary, genetic, and secondary types, although these subcategories probably encompass significantly diverse pathogeneses. Here, we pe...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD058875 | Pride
Serpina1 Pfsgs Proteomics Tmt Par1 Proteases Zebrafish Dda 
GenomicsExon Level Expression Profiling of Focal Segmental glomerulosclerosis (FSGS)
Exon Level Expression Profiling of Focal Segmental glomerulosclerosis (FSGS)
PRJNA533313 | ENA
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