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TranscriptomicsTowards understanding breast cancer mechanisms to metastasize
How organ-specific metastatic traits accumulate in primary tumors remains unknown. We identified a role of the primary tumor stroma in selecting breast cancer cells that are primed for metastasis in the bone. A fibroblast-rich stroma in breast tumors creates a microenvironment that is similar to tha...
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-47389 | biostudies-arrayexpress
ProteomicsIntegrative analysis of genomics and proteomics data on clinical breast cancer tissue specimens extracted with acid guanidinium thiocyanate-phenol-chloroform
Acid guanidinium thiocyanate, phenol and chloroform extraction (AGPC) is a commonly used procedure to extract RNA from fresh frozen tissues and cell lines. In addition, DNA and proteins can be recovered, which makes AGPC an attractive source for integrative analysis on tissues of which little materi...
ORGANISM(S): Homo sapiens (Human) 
2016-06-24 | PXD001533 | Pride
Proteogenomics Acid guanidinium phenol-chloroform Shotgun proteomics Rna bee Breast cancer Sample preparation 
UnknownSelection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.
Not available
S-EPMC3974915 | biostudies-literature
TranscriptomicsTamoxifen-resistant human breast cancer cell lines
A functional genetic screen to identify genes causing tamoxifen resistance in an estrogen-dependent human breast cancer cell model was performed. By insertion of defective retrovirus into the genome, individual genetic changes were introduced at random in ZR-75-1 cells. Subsequently, infected cells ...
ORGANISM(S): Homo sapiens 
2009-12-09 | E-GEOD-14513 | biostudies-arrayexpress
UnknownA kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy.
Not available
S-EPMC6604188 | biostudies-literature
UnknownTranscription profiling of human breast cancer samples - relapse free survival
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-2034 | biostudies-other
UnknownLatent bone metastasis in breast cancer tied to Src-dependent survival signals.
Not available
S-EPMC2749247 | biostudies-literature
UnknownTamoxifen-resistant human breast cancer cell lines
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-14513 | biostudies-other
UnknownLung metastasis genes couple breast tumor size and metastatic spread.
Not available
S-EPMC1871856 | biostudies-literature
UnknownThe 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.
Not available
S-EPMC4995039 | biostudies-literature
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