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Identification of FOLR1-interacting proteins in Xenopus laevis embryos during neurulation.
ORGANISM(S): Xenopus laevis (African clawed frog) 
2024-02-26 | PXD048476 | Pride
Expression data (mRNA) from GD-9.5 (E9.5), Folr1+/+ (Folr1 WT) and Folr-/- (Folr1 KO) mouse embryos
Folic acid is a nutrient essential for embryonic development. Folate deficiency can cause embryolethality or neural tube defects and orofacial anomalies. Folate receptor 1 (Folr1), is a folate binding protein that facilitates the cellular uptake of dietary folate. Animal studies highlighted critical...
ORGANISM(S): Mus musculus 
2021-02-10 | GSE155428 | GEO
Dolutegravir induces FOLR1 expression during brain organoid development.
Defective function of FolR1 in mice results in inadequate transport, accumulation, or metabolism of folate during cardiovascular morphogenesis. We have observed cardiovascular abnormalities including outflow track defects and aortic arch artery defects in these genetically compromised mice. In order...
ORGANISM(S): Mus musculus 
2006-02-20 | GSE3487 | GEO
Defective function of FolR1 in mice results in inadequate transport, accumulation, or metabolism of folate during cardiovascular morphogenesis. We have observed cardiovascular abnormalities including outflow track defects and aortic arch artery defects in these genetically compromised mice. In order...
ORGANISM(S): Mus musculus 
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