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TranscriptomicsRole of TAZ as mediator of Wnt signaling (SW480)
To investigate the role of TAZ downstream of the abberrant Wnt signaling in CRC cells, we compared the expression profiles of parental SW480 cells (empty vector) transfected with siControl, siTAZ, sibeta-catenin or reconstituted with wild type APC and transfected with siControl Keywords: expression...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-39904 | biostudies-arrayexpress
TranscriptomicsRole of TAZ as mediator of Wnt signaling (MII)
To investigate the role of TAZ downstream of APC and beta-catenin in mammary epithelial cells cells, we compared the expression profiles of MCF10-T1k (MII) cells transfected with siControl, siAPC, siAPC+siTAZ, sibeta-catenin, or sibeta-catenin+siTAZ. Keywords: expression profiling by array We colle...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-39902 | biostudies-arrayexpress
TranscriptomicsComparative genomics reveals new molecular targets for accelerated strain improvement of rifamycin B-producing strains
In the present study, we have used a genomic approach to understand how the classical mutate-and-screen method actually generated an improved rifamycin B producer. Compared with the reference strains Amycolatopsis mediterranei S699 (rifamycin B producer) and U32 (rifamycin SV producer), a total of 2...
ORGANISM(S): Amycolatopsis mediterranei S699 
2014-08-26 | E-GEOD-51015 | biostudies-arrayexpress
GenomicsWidespread association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth [ChIP-Seq]
The goal of this study was to identify YAP/TAZ direct transcriptional targets and transcriptional partners, through ChIP-sequencing and gene expression profiling. ChIP-seq analysis of YAP, TAZ, TEAD4 and JUN in MDA-MB-231 cells. Two independent replicates were analysed for each TF, as well as for ne...
ORGANISM(S): Homo sapiens 
2015-08-03 | E-GEOD-66081 | biostudies-arrayexpress
TranscriptomicsCircadian transcriptome of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO and control Cre- littermates
To investigate the role of the circadian clock gene Bmal1 in skeletal muscle, we compared the circadian transcriptomes of fast tibialis anterior (TA) and slow soleus (SOL) skeletal muscles from muscle-specific Bmal1 KO (mKO) and their control Cre- littermates (Ctrl). Keyword: Circadian Transcriptome...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-43071 | biostudies-arrayexpress
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