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TranscriptomicsLactobacillus acidophilus and Helicobacter pylori stimulation of bone marrow derived macrophage
Helicobacter pylori causes chronic gastritis and avoids elimination by the immune system of the infected host. The commensal bacterium Lactobacillus acidophilus has been reported to exert beneficial effects as a supplement during H. pylori eradication therapy. In the present study, we applied whole ...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-42622 | biostudies-arrayexpress
ProteomicsRelative protein quantification in mouse hippocampal synaptosomes during aging series
Age-related cognitive decline is a serious health concern in our aging society. Decreased cognitive function observed during healthy brain aging is most likely caused by changes in brain connectivity and synaptic dysfunction in particular brain regions. Here we show that aged C57BL/6J wildtype mice ...
ORGANISM(S): Mus musculus (Mouse) 
2014-09-10 | PXD001135 | Pride
Natural aging Mouse Itraq Hippocampus Synaptosome 
TranscriptomicsSilencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape mechanisms
Breast cancer metastasis to bone is a critical determinant of long-term survival after treatment of primary tumors. We used a mouse model of spontaneous bone metastasis to determine new molecular mechanisms. Differential transcriptome comparisons of primary and metastatic tumor cells revealed that a...
ORGANISM(S): Mus musculus 
2012-07-17 | E-GEOD-37828 | biostudies-arrayexpress
TranscriptomicsStructural basis of a novel Interferon b signaling axis mediated via the ifnar1 receptor
Type I interferons (IFNs) are a family of cytokines that play an important role in regulating immune responses to pathogens and tumors and are used therapeutically. All IFNs are considered to signal via the heterodimeric IFNAR1-IFNAR2 complex, yet some subtypes such as IFN? can exhibit distinct fun...
ORGANISM(S): Mus musculus 
2013-07-13 | E-GEOD-48827 | biostudies-arrayexpress
UnknownEmergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohort.
Not available
S-EPMC3008652 | biostudies-literature
TranscriptomicsTgFVB vs FVB 6 and 8 week kidneys
Human Immunodeficiency Virus (HIV) associated nephropathy (HIVAN) is characterized clinically by both nephrosis and by rapidly progressive kidney dysfunction. HIVAN is characterized histologically by both collapsing focal segmental glomerulosclerosis and prominent tubular damage. Neutrophil Gelatina...
ORGANISM(S): Mus musculus 
2009-12-25 | E-GEOD-14221 | biostudies-arrayexpress
Genomicsena-DATASET-SC-21-07-2014-10:55:39:527-89 - samples
NSCLC targeted.
EGAD00001000889 | EGA
Genomicsena-DATASET-SC-21-07-2014-10:52:30:961-88 - samples
NSCLC WGS.
EGAD00001000888 | EGA
Genomicsena-DATASET-GENE-CAO-08-02-2016-11:04:25:039-253 - samples
Multi-region Illumina whole-exome and/or whole-genome sequencing on tumor regions collected from early-stage NSCLC patients who underwent definitive surgical resection prior to receiving adjuvant therapy. Patients covered by this dataset: L012, L013, L015, L017
EGAD00001001918 | EGA
Genomicsena-DATASET-TRACERX-25-07-2014-12:27:19:910-271 - samples
Multi-region Illumina whole-exome and/or whole-genome sequencing on tumor regions collected from early-stage NSCLC patients who underwent definitive surgical resection prior to receiving adjuvant therapy. Detected variants were validated on Ion AmpliSeq™ Custom Panel and/or Comprehensive Cancer Gen...
EGAD00001000900 | EGA
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