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The Sahel/Savannah belt harbours diverse populations with different demographic histories and different subsistence patterns. However, populations from this large African region are notably under-represented in genomic research. To investigate the population structure and adaptation history of popul...
ORGANISM(S): Homo sapiens 
In this work we present the PrPC-dependent gene expression signature in N2A cells and its implication on the most overrepresented functions; cell cycle, cell growth and proliferation and cell morphology. To evaluate the genes whose transcription was regulated after Prnp modulation, RNA samples were ...
ORGANISM(S): Mus musculus 
Natural genetic variation is the raw material of evolution and influences disease development and progression. To analyze the effect of the genetic background on protein expression in the nematode C. elegans (Caenorhabditis elegans), the two genetically highly divergent wild-type strains N2 (Bristol...
ORGANISM(S): Caenorhabditis elegans 
2016-03-11 | PXD002010 | Pride
Interferons (IFNs) are key players in the antiviral response. IFN sensing by the cell activates transcription of IFN-stimulated genes (ISGs) able to induce an antiviral state by affecting viral replication and release. IFN also induces the expression of ISGs that function as negative regulators to l...
ORGANISM(S): Homo sapiens 
The study aims to describe the differential spatial distrubution of secondary metabolites in different grape species,. The aims is to describe the characteristics that differentiate wild grapes from good quality vinifera grapes, understand the limits and advantages from both classes.
2017-01-23 | MTBLS209 | MetaboLights
Vitis vinifera berries are sensitive towards infection by the necrothopic pathogen Botrytis cinerea leading to important economic losses worldwide. The combined analysis of the transcriptome and metabolome associated with the infection has not been previously performed in grapes or in another fleshy...
ORGANISM(S): Vitis vinifera 
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