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TranscriptomicsMFAP4 is an integrin M-NM-1VM-NM-23/5 ligand involved in vascular remodeling
Arterial injury or occlusive arterial disease may stimulate healing responses, which when overexuberant, leads to restenosis of the injured vessel. This response is influenced by specific integrin signalling in vascular smooth muscle cells (VSMCs). Microfibril-associated protein 4 (MFAP4) colocates ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-40480 | biostudies-arrayexpress
MetabolomicsInorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803
The amount of inorganic carbon represents one of the main environmental factors determining productivity of photoautotrophic organisms. Using the model cyanobacterium Synechocystis sp. PCC 6803, we performed a first metabolome study with cyanobacterial cells shifted from high CO2 (5% in air) into co...
2015-09-14 | MTBLS5 | MetaboLights
UnknownForaging in a dynamic environment: Response of four sympatric sub-Antarctic albatross species to interannual environmental variability.
Not available
S-EPMC7593157 | biostudies-literature
TranscriptomicsA broad phenotypic screen identifies novel dominant phenotypes in Huntington’s disease CAG knock-in mice
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder characterized by abnormal voluntary and involuntary movements, cognitive impairment and psychiatric disturbances. In order to identify phenotypic changes in the mouse that are most likely to be relevant to events triggere...
ORGANISM(S): Mus musculus 
2011-09-30 | E-GEOD-28232 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Dll1 mutant mouse lines on different genetic background
The evolutionarily conserved Delta-Notch cell-cell signal-transduction pathway regulates the determination of various cell fates, which are important for the morphogenesis and development of numerous organs and tissues in many vertebrates and invertebrates. The Dll1 gene was mutated by homologous r...
ORGANISM(S): Mus musculus 
2009-01-01 | E-GEOD-11867 | biostudies-arrayexpress
TranscriptomicsTomato colonization by wt R. solanacearum and a hrp mutant
Tomato seeds (Solanum lycopersicum Mill., cultivar Marion) were germinated in vermiculite and 10-day old seedlings were transplanted into 4-inch plastic pots containing a mixture of composted pine bark and vermiculite (3:1) amended with lime and fertilizer. Plants were incubated in a growth chamber ...
ORGANISM(S): Solanum lycopersicum Solanum tuberosum 
2007-09-01 | GSE8212 | GEO
TranscriptomicsMycobacteria-Dependent Expression of microRNA-142-3p Reduces WASP Family Proteins and Controls Phagocytosis
Phagocytosis requires the activation of a plethora of mechanisms that include the activation of the actin cytoskeleton guided by the Arp2/3 complex. These are promoted by activators such as the Wiskott Aldrich Syndrome Protein (WASP) family members. In order to further understand the molecular mecha...
ORGANISM(S): Mus musculus 
2013-06-16 | E-GEOD-23429 | biostudies-arrayexpress
TranscriptomicsAbcb4 liver expression profiling
The multidrug resistance gene 2 (Mdr2 or Abcb4) encodes a P-glycoprotein (Pgp) - a phospholipid flippase - that is the murine orthologue of the MDR3 gene in humans. The MDR2 protein is principally expressed in the bile canalicular membrane of the liver. A homozygous disruption of Abcb4 causes absenc...
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-26699 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Dll1 mutant mouse line
BACKGROUND: The Notch signaling pathway is an evolutionary conserved signal transduction pathway involved in embryonic patterning and regulation of cell fates during development and self-renewal. Recent studies have demonstrated that this pathway is integral to a complex system of interactions, invo...
ORGANISM(S): Mus musculus 
2009-03-01 | E-GEOD-12954 | biostudies-arrayexpress
TranscriptomicsExpression profiling analysis of NOX4 mutant mouse model
NADPH oxidases are the only know enzyme family that has reactive oxygen species (ROS, e.g. superoxide and hydrogen peroxide) as their main metabolic product. They are therefore a prima candidate gene family to define a molecular source for ROS in physiology and pathophysiology. The type 4 NADPH oxid...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-20400 | biostudies-arrayexpress
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