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UnknownHigh-resolution structure of RGS17 suggests a role for Ca2+ in promoting the GTPase-activating protein activity by RZ subfamily members.
Not available
S-EPMC6527179 | biostudies-literature
ProteomicsStaphylococcus aureus USA300 LAC and XdrA mutant strain, secretome, Exponential phase, Stationary phase, LC-MS/MS, Orbitrap
The success of Staphylococcus aureus as a pathogen results from the production of a wealth of virulence determinants that aid in immune evasion, host cell invasion and dissemination of infection. Given the niche specific roles of these factors in infection, their production is controlled by a comple...
ORGANISM(S): Staphylococcus aureus 
2022-04-08 | PXD026577 | Pride
Xdra Bacteria Mid exponential growth phase Orbitrap Staphylococcus aureus Pathogenesis Lc-ms/ms 
ProteomicsAstrocyte-Oligodendrocyte interaction regulates central nervous system regeneration
Failed regeneration of myelin around neuronal axons following central nervous system damage contributes to nerve dysfunction and clinical decline in various neurological conditions, for which there is an unmet therapeutic demand. Here, we show that interaction between glial cells – astrocytes and ma...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-17 | PXD041850 | Pride
Central nervous system Nrf2 Myelin Oligodendrocyte Astrocyte 
UnknownExtended Prophylaxis With Nevirapine Does Not Affect Growth in HIV-Exposed Infants.
Not available
S-EPMC6817404 | biostudies-literature
UnknownFeasibility and safety of ALVAC-HIV vCP1521 vaccine in HIV-exposed infants in Uganda: results from the first HIV vaccine trial in infants in Africa.
Not available
S-EPMC3625520 | biostudies-literature
UnknownEfficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): a randomised, double-blind, placebo-controlled trial.
Not available
S-EPMC3539769 | biostudies-literature
UnknownEfficacy and safety of an extended nevirapine regimen in infants of breastfeeding mothers with HIV-1 infection for prevention of HIV-1 transmission (HPTN 046): 18-month results of a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC3945386 | biostudies-literature
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
UnknownCanadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings.
Not available
S-EPMC12320028 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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