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ProteomicsFpa (YlaN) is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in Staphylococcus aureus via a direct interaction.
Iron (Fe) is a trace nutrient required by nearly all organisms. As a result of the demand for Fe and the toxicity of non-chelated cytosolic ionic Fe, regulatory systems have evolved to tightly balance Fe acquisition and usage while limiting overload. In most bacteria, including the mammalian pathoge...
ORGANISM(S): Staphylococcus aureus 
2025-05-06 | PXD051930 | Pride
Sulfur Staphylococcus aureus Fpa Iron Fur Ylan 
ProteomicsProteomic analysis of FPA interactors
Genes involved in disease resistance are some of the fastest evolving and most diverse components of genomes. Large numbers of nucleotide-binding, leucine-rich repeat receptor genes (NLRs) are found in plant genomes and provide disease resistance. However, NLRs can trigger autoimmunity, disrupt bene...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-12-16 | PXD022684 | Pride
Transcription Arabidopsis Fpa Rna processing 
GenomicsGenome-wide occupancy of BDR1, BDR2 and FPA (ChIP-seq)
Genome-wide occupancy of BDR1, BDR2 and FPA (ChIP-seq)
PRJNA449914 | ENA
GenomicsIllumina RNA-Seq of FPA mutants
Illumina RNA-Seq of FPA mutants and Overexpressors
PRJEB41455 | ENA
GenomicsGenome-wide occupancy of BDR1, BDR2 and FPA (ChIP-seq)
We generated Arabidopsis lines expressing tagged (3X Myc tag) versions of BDR1 or BDR2 driven by their endogenous promoters on a bdrs triple mutant background (bdrs: cross of bdr1/AT5G25520 mutant SALK_142108C, bdr2/AT5G11430 mutant CS852350 and bdr3/AT2G25640 mutant SALK_059905). The genome-wide di...
ORGANISM(S): Arabidopsis thaliana 
2019-08-08 | GSE113059 | GEO
UnknownTranscription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.
Not available
S-EPMC3814327 | biostudies-literature
GenomicsNanopore direct RNA sequencing of FPA mutants
Nanopore direct RNA sequencing of FPA mutants and overexpressors
PRJEB41451 | ENA
GenomicsGene expression profiling in wild-type, fpa mutant and bdrs triple mutant Arabidopsis seedlings
Gene expression profiling in wild-type, fpa mutant and bdrs triple mutant Arabidopsis seedlings
PRJNA446047 | ENA
UnknownCrystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA.
Not available
S-EPMC4981400 | biostudies-literature
TranscriptomicsGene expression profiling in wild-type, fpa mutant and bdrs triple mutant Arabidopsis seedlings
We analyzed by RNA-seq the transcriptome of 8-day old Arabidopsis thaliana seedlings for wild-type (Col-0), single mutant for FPA (fpa/AT2G43410, line fpa-7) or a triple mutant of all three BDR proteins (bdrs: cross of bdr1/AT5G25520 mutant SALK_142108C, bdr2/AT5G11430 mutant CS852350 and bdr3/AT2G2...
ORGANISM(S): Arabidopsis thaliana 
2019-08-08 | GSE112440 | GEO
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