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ProteomicsOn tissue Top down microproteomic bridged to MALDI MS Imaging reveal the molecular physiome of brain regions
Tissue Top-down microproteomic was performed on 3 brain regions. 156 references proteins from different cellular compartments were characterized. Moreover, 11 Alternative proteins issued from alternative open reading frames (AltORF) were identified and were relied to the brain regions and associated...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-11-14 | PXD005424 | Pride
Alternative proteins Top down micro-proteomics Maldi imaging 
ProteomicsATP MODIFIES THE PROTEOME OF EXTRACELLULAR VESICLES RELEASED BY MICROGLIA AND INFLUENCES THEIR ACTION ON ASTROCYTES
Extracellular ATP is among molecules promoting microglia activation and inducing the release of extracellular vesicles (EVs), which are potent mediators of intercellular communication between microglia and the microenvironment. We previously showed that EVs produced under ATP stimulation (ATP-EVs) p...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD007650 | Pride
Proteomics Extracellular vesicles Microglia Atp Astrocyte activation 
ProteomicsOvarian serous cancer tumor microenvironment investigated by MALDI MSI associated to Top-down microproteomic: Evidence of a hidden proteome as novel potential target
Top-down tissue microproteomic was performed in order to investigate tumoral tissue microenvironment. 289 proteins with post-translational modifications have been isolated from biospies including Tumor, Borderline and healthy regions of serous ovarian cancers. Tumor tissue displays a majority of pro...
ORGANISM(S): Homo sapiens (Human) 
2017-06-23 | PXD005420 | Pride
Alternative proteins Top down micro-proteomics Maldi imaging 
ProteomicsA specific lipid metabolic profile is associated with the epithelial mesenchymal transition program
Several studies have identified a specific metabolic program that is associated with the process of epithelial-mesenchymal transition (EMT). Whereas much is known about the association between glucose metabolism and EMT, the contribution of lipid metabolism is not still completely understood. Here, ...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD011854 | Pride
Epithelial mesenchymal transition Metabolism Lipids Mass spectrometry Β-catenin 
TranscriptomicsTranscriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the murine ovarian follicles.
Cumulus cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were co...
ORGANISM(S): Mus musculus 
2012-10-14 | E-GEOD-36604 | biostudies-arrayexpress
TranscriptomicsSMARCB1-deficient rhaboid tumors of the kidney and renal medullary carcinomas.
We used microarrays to compared gene expression profilings in various tumors of the kidney. [human mRNA] 8 human RTK, 5 human RMC.
ORGANISM(S): Homo sapiens 
2016-03-08 | E-GEOD-70421 | biostudies-arrayexpress
Genomicsena-DATASET-ICM-15-06-2017-11:25:49:785-1367 - samples
Description not provided
EGAD00001003382 | EGA
Genomicsena-DATASET-ICM-15-06-2017-21:23:23:822-1522 - samples
Description not provided
EGAD00001003387 | EGA
GenomicsSame-day genomic and epigenomic diagnosis of brain tumors using realtime nanopore sequencing
Molecular classification of cancer has entered clinical routine to inform diagnosis, prognosis and treatment decisions. At the same time, new tumor entities have been identified that cannot be defined histologically. For central nervous systems tumors, the current World Health Organization classific...
EGAS00001002213 | EGA
MetabolomicsAcute heat stress amplifies exercise-induced metabolomic perturbations and reveals variation in circulating amino acids in endurance-trained males

Using untargeted metabolomics, we aimed to characterise the systemic impact of environmental heat stress during exercise. Twenty-three trained male triathletes completed a 30-min exercise test in hot (35°C) and temperate (21°C) conditions. Venous blood samples were collected immediately pre- and ...

2025-08-14 | MTBLS6051 | MetaboLights
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