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A ‘Cartes d’Identite des Tumeurs’ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 56 glioblastomas |Submitter : Aurelien de Reynies | Project leader : Francois Berger
ORGANISM(S): Homo sapiens 
The stringent response is initiated by rapid (p)ppGpp synthesis, which leads to a profound reprogramming of gene expression in most bacteria. The stringent phenotype seems to be species specific and may be mediated by fundamentally different molecular mechanisms. In Staphylococcus aureus, (p)ppGpp s...
ORGANISM(S): Staphylococcus aureus 
Distinct functions mediated by members of the MOB family of proteins remain elusive beyond the evolutionary conserved and well-established roles of MOB1A and B in regulating the Hippo pathway. Since MOB proteins are adaptors, understanding how they engage in protein-protein interactions and complexe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-11 | MSV000092406 | MassIVE
Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification within transcribed regions, but it remains uncertain how these modifications influence, or are influenced by, properties of the elongation complex. Here we establish an intimate link betw...
ORGANISM(S): Schizosaccharomyces pombe 
Female mosquitoes fed with blood infected with two alternative P. berghei strains: wild type (wt) or an invasion-deficient, CTRP (Circumsporozoite- and TRAP-related protein) knockout (ko) strain. We used CTRPko-infected midguts as reference, as they experience pre-invasion conditions similar to thos...
ORGANISM(S): Anopheles gambiae 
This dataset comprises bulk RNA sequencing (RNA-seq) data generated from primary human brain microvascular endothelial cells (HBMECs), induced pluripotent stem cell (iPSC)-derived iBMEC-like cells, and ETS-transcription factor-guided iPSC-derived endothelial cells (ETS-iBMEC). Cells were cultured as...
ORGANISM(S): Homo sapiens 
Poly(ADP-ribose) polymerase 3 (PARP3) is a member of the PARP family of enzymes. It is structurally related to the well characterized type member PARP1 that orchestrates DNA strand break repair and cell death by the synthesis of poly(ADP-ribose). In contrast, the functions of PARP3 are undefined. We...
ORGANISM(S): Homo sapiens 
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