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ProteomicsDIA of Gasdermin-D knockout and cuprizone treated mouse brain tissue
Data-independent acquisition (DIA) of four replicates of mouse brain tissue lysate for each of the four conditions Gasdermin-D WT, Gasdermin-D KO, Gasdermin-D WT treated with cuprizone, and Gasdermin-D KO treated with cuprizone.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-02-02 | MSV000091185 | MassIVE
MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
UnknownEffect of Antimicrobial Prophylaxis on Corynebacterium bovis Infection and the Skin Microbiome of Immunodeficient Mice.
Not available
S-EPMC9084569 | biostudies-literature
GenomicsLinking genes, genomic instability and molecular subgroups in medulloblastoma
Brain tumors are the second most common pediatric cancer and carry the highest mortality rates in this age group. Medulloblastoma is the most frequent malignant brain tumor of childhood. Recent studies indicate that medulloblastoma comprises at least four sub-entities (SHH-signaling, WNT-signali...
EGAS00001000085 | EGA
TranscriptomicsAltered interactions between the gut microbiome and colonic mucosa precede polyposis in APCMin/+ mice
Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...
ORGANISM(S): Mus musculus 
2015-08-24 | E-GEOD-67634 | biostudies-arrayexpress
ProteomicsA global Staphylococcus aureus proteome resource applied to the in vivo characterization of host- pathogen interactions
1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435) 2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 (ncbitaxon:93061) Homo Sapiens (ncbitaxon:9606) 
2018-06-21 | MSV000082483 | MassIVE
ProteomicsPeptide centric detection of cross-linked peptides using PASEF, MeroX, and Skyline
Cross-linking mass spectrometry (XL-MS) has evolved into a pivotal technique for probing protein interactions, with recent ad-vancements significantly enhancing its analytical potential. This technical note presents advancements in cross-linking mass spec-trometry (XL-MS) through the implementation ...
ORGANISM(S): Bos Taurus 
2024-05-13 | PXD047307 | panorama
TranscriptomicsTranscription profiling of mouse WT and Cav-3 knockouts on FVB/N genetic background mammary glands reveals loss of caveolin-3 induces the development of a lactogenic microenvironment
Here, we show that functional loss of a single gene is sufficient to confer constitutive milk protein production and protection against mammary tumor formation. Caveolin-3 (Cav-3), a muscle-specific caveolin-related gene, is highly expressed in striated and smooth muscle cells. We demonstrate that C...
ORGANISM(S): Mus musculus 
2009-01-31 | E-GEOD-12881 | biostudies-arrayexpress
ProteomicsCouzens_Hippo_P86_VS4
Not available
2013-06-28 | MSV000078450 | MassIVE
GenomicsEGAS00000000046-ega-20110530 - samples
ICGC Germany PedBrain Medulloblastoma Pilot_2_LM
EGAD00001000027 | EGA
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