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TranscriptomicsGene expression changes associated with progression of Irf8M-bM-^@M-^S/M-bM-^@M-^S CML-like disease into blast crisis after M-NM-2-catenin activation
Progression and disease relapse of chronic myeloid leukemia (CML) depends on leukemia-initiating cells (LIC) that resist treatment. Using mouse genetics, we observed that compound constitutive activation of M-NM-2-catenin and deletion of Irf8 results in progression of CML-like disease into fatal bla...
ORGANISM(S): Mus musculus 
2013-09-26 | E-GEOD-49054 | biostudies-arrayexpress
MetabolomicsMetabolic Profiling of Volatile Organic Compounds (VOCs) Emitted by the Pathogens Francisella tularensis and Bacillus anthracis in Liquid Culture
We conducted comprehensive (untargeted) metabolic profiling of volatile organic compounds (VOCs) emitted in culture by bacterial taxa Francisella tularensis (F. tularensis) subspecies novicida and Bacillus anthracis (B. anthracis) Sterne, surrogates for potential bacterial bioterrorism agents, as we...
2020-08-20 | MTBLS1737 | MetaboLights
UnknownStochastic block coordinate Frank-Wolfe algorithm for large-scale biological network alignment.
Not available
S-EPMC4826425 | biostudies-literature
TranscriptomicsComparative analysis of D. shibae wild-type vs. M-bM-^HM-^FctrA, M-bM-^HM-^FchpT and M-bM-^HM-^FcckA
Comparison of D. shibae wild-type with single gene knock-out strains of a phosphorelay conserved in Alphaproteobacteria (M-bM-^HM-^FctrA, M-bM-^HM-^FchpT and M-bM-^HM-^FcckA) Loop-design, two biological replicates of D. shibae wild-type, M-bM-^HM-^FctrA, M-bM-^HM-^FchpT and M-bM-^HM-^FcckA in mid-ex...
ORGANISM(S): Dinoroseobacter shibae DFL 12 
2013-05-30 | E-GEOD-47451 | biostudies-arrayexpress
UnknownFirst-row transition metal doped germanium clusters Ge16M: some remarkable superhalogens.
Not available
S-EPMC9068264 | biostudies-literature
MetabolomicsInhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells

BACKGROUND: Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall survival rate of high-risk disease remai...

2022-11-30 | MTBLS858 | MetaboLights
ProteomicsDifferent expressed proteins of HIV-infected long-term non-progressors (LTNPs) and regular progressors (RPs)
The whole blood samples were obtained from 3 LTNPs and 2 RPs HIV-1 infected patients, and the CD4+ T cells were isolated using anti-CD4-specific antibody-coated microbeads (130-045-101, Miltenyi Biotec, Germany) according to the manufacturer's instructions. Then the proteins extracted from the CD4+ ...
ORGANISM(S): Homo Sapiens 
2023-10-12 | PXD046078 |
TranscriptomicsaSyn polyA-RNAseq in PD and unaffected cortical brain samples
We sought to more precisely characterize the different alpha-synuclein (aSyn) 3M-bM-^@M-^YUTR mRNA species in normal and PD human brain. High-throughput, whole-transcriptome sequencing of the 3M-bM-^@M-^YUTR ends of polyadenylated mRNA transcripts (termed pA-RNAseq; see Methods) was performed on a ...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-40710 | biostudies-arrayexpress
UnknownMore legislation, more violence? The impact of Dodd-Frank in the DRC.
Not available
S-EPMC6084930 | biostudies-literature
UnknownClonal dissemination of a CTX-M-15 beta-lactamase-producing Escherichia coli strain in the Paris area, Tunis, and Bangui.
Not available
S-EPMC1489776 | biostudies-literature
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