Frankel Gad G - OmicsDI

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The Rab-binding profiles of Legionella effectors

Legionella pneumophila, the causative agent of Legionnaire’s disease, uses its type IV secretion system to translocate over 300 effector proteins into host cells. These effectors subvert host cell signaling pathways to ensure bacterial proliferation. Despite their importance for pathogenesis, the ro...

ORGANISM(S): Homo sapiens (Human)

2016-02-11 | PXD003573 | Pride

Defining targets of the bacterial ADP-ribosyltransferase EspJ

Tyrosine phosphorylation is key for signal transduction from exogeneous stimuli, including the defence against pathogenic microbes. Pathogens have acquired mechanisms to subvert protein phosphorylation as a means to control host immune responses and facilitate invasion and dissemination. The bacteri...

ORGANISM(S): Homo sapiens (Human)

2018-03-16 | PXD008533 | Pride

Ehec Human Adp-ribosyltransferase Lc-ms/ms

Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM 12 mice reveals pathogen-specific host and microbiota responses

Campylobacter jejuni, non-typhoidal Salmonella spp., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model EPEC and EHEC infection ...

2025-02-25 | MTBLS11078 | MetaboLights

Control of Virulence Gene Expression in Citrobacter rodentium by Trascription Factor RegA

Identification of the targets of RegA with and without bicarbonate stimulation by comparing RegA knockout to multicopy RegA transgenics. RegA is an AraC like transcription factor identified in a mutational screen for virulence genes in Citrobacter rodentium, an attaching and effacing pathogen that ...

ORGANISM(S): Citrobacter rodentium

2010-05-19 | E-GEOD-12876 | biostudies-arrayexpress

Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study.

Not available

S-EPMC7755038 | biostudies-literature

Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial.

Not available

S-EPMC3596060 | biostudies-literature

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.

Not available

S-EPMC9621702 | biostudies-literature

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.