Sort   by:  
 Page size 
TranscriptomicsTranscription profiling by array of Legionella pneumophila ppGpp knockout and relA over expression mutants.
Effect of ppGpp on transcript level after RelA overexpression (90 min). The cells are constructed in our lab. They are knock-out mutants in the production of ppGpp(guanosine tetraphosphate) of Legionella, complemented with an over-expression vector containing the relA gene to express the RelA prot...
ORGANISM(S): Legionella pneumophila 
2010-04-14 | E-MTAB-211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Legionella pneumophilaEfter RelA overexpression.
Effect of ppGpp on transcript level after RelA overexpression (45 min). The cells are constructed in our lab. They are knock-out mutants in the production of ppGpp(guanosine tetraphosphate) of Legionella, complemented with an over-expression vector containing the relA gene to express the RelA prot...
ORGANISM(S): Legionella pneumophila 
2010-04-13 | E-MTAB-222 | biostudies-arrayexpress
ProteomicsMolecular Characterization of LubX. AP-MS using Legionella lysate
Legionella pneumophila delivers over 300 effector proteins into the host cytosol. One of these effectors, LubX contains 2 U-box domains, and directs the proeosomal degradation of another translocated protein, SidH, however this 'metaeffector' activity is pooly understood. As part of our investigatio...
ORGANISM(S): Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) 
2020-01-27 | PXD001525 | Pride
Sidh Ap-ms Dits Ltq xl Lubx Legionella 
TranscriptomicsStrand specific sequencing illustrates the complex transcriptional response of Legionella pneumophila during infection
Legionella pneumophila is a Gram-negative facultative intracellular human pathogen with a distinct biphasic lifestyle. One of its primary environmental hosts in the free-living amoeba Acanthamoeba castellanii and its infection by L. pneumophila mimics that seen in human macrophages. Here we present ...
ORGANISM(S): Legionella pneumophila 
2011-02-11 | E-GEOD-27232 | biostudies-arrayexpress
ProteomicsInteractome of the Legionella pneumophila effector PieE
The in vivo interactome of the Legionella pneumophila effector PieE reveals binding to multiple Rab GTPases
ORGANISM(S): Legionella pneumophila 
2017-02-08 | PXD000706 | Pride
Legionella pneumophila 
ProteomicsDevelopment of covalent probes to capture Legionella pneumophila effector enzymes
Upon infection of host cells Legionella pneumophila releases a multitude of effector enzymes into the hosts cytoplasm that hijack a plethora of cellular activities, including the hosts ubiquitination pathways. Effectors belonging to the SidE-family are involved in non-canonical serine phosphoribosyl...
ORGANISM(S): Homo sapiens (Human) Legionella pneumophila subsp. pneumophila Lp02 
2025-05-06 | PXD049797 | Pride
Legionella pneumophila Activity-based probe Ubiquitylation Adp-ribosylation Bacterial infection 
ProteomicsLegionella pneumophila proteome
Legionella pneumophila cells were harvested during exponential growth (RP) and stationary growth (TP). VBNC cells were also anylzed. Protein subfractions were studied.
ORGANISM(S): Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) 
2015-11-13 | PXD001926 | Pride
Whole cell proteome Extracellular proteome Legionella Surface proteome 
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. the L. pneumophila delta DotA mutant 24h p.i.
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila was investigated using DNA microarrays. A detailed analysis of the 24 h time point post infection was performed in comparison to three controls, uninfected cells and co-incubation with Legionella hac...
ORGANISM(S): Dictyostelium discoideum 
2013-09-07 | E-GEOD-50536 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. L. hackeliae 24h p.i.
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila was investigated using DNA microarrays. A detailed analysis of the 24 h time point post infection was performed in comparison to three controls, uninfected cells and co-incubation with Legionella hac...
ORGANISM(S): Dictyostelium discoideum 
2013-09-07 | E-GEOD-50651 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 24h p.i. (comparison experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila was investigated using DNA microarrays. A detailed analysis of the 24 h time point post infection was performed in comparison to three controls, uninfected cells and co-incubation with Legionella hac...
ORGANISM(S): Dictyostelium discoideum 
2013-09-11 | E-GEOD-50696 | biostudies-arrayexpress
Sort   by:  
 Page size