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Psoriasis cases as part of WTCCC2 phase 2
To identify novel susceptibility loci for psoriasis, we undertook a genome-wide association scan of of 594,224 SNPs in 2,622 individuals with psoriasis and 5,667 controls.
The PHACTR1 gene to a range of vascular and neurological diseases, underscoring its pivotal role in biology. As part of a larger multi-omics study, we performed bulk RNA-seq on stable HT1080 cell lines with overexpression or knockdown of PHACTR1, comparing them to scrambled control cells, to underst...
ORGANISM(S): Homo sapiens 
Pressure overload-induced cardiac hypertrophy was examined in IL-18 knockout and littermate control mice. Experiment Overall Design: 4 groups with RNA pooled from 5-6 per group. Role of IL-18 on gene expression in cardiac hypertrophy induced by pressure overload (transaortic constriction)
ORGANISM(S): Mus musculus 

While rapid progress has been made to characterize the bacterial and archaeal populations of the rumen microbiome, insight into how they interact with keystone protozoal species remains elusive. Here, we reveal two distinct rumen community types (RCT-A and RCT-B) that are not strongly associated ...

2025-06-11 | MTBLS12283 | MetaboLights
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
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