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MetabolomicsMirabegron displays anticancer effects by globally browning adipose tissues

Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development by targeting adipose metabolism remain larg...

2023-11-08 | MTBLS8682 | MetaboLights
TranscriptomicsQuantitative Expression Profiling of RNA from Formalin-Fixed, Paraffin-Embedded (FFPE)and Fresh Frozen (FF) Breast Cancer samples
Unluckily, FFPE archival methods lead to partial RNA degradation, limiting the amount of derivable information. This study aims to evaluate if the DASL gene expression assay, designed to generate reproducible data from degraded RNAs, is a reliable method to apply on RNA from FFPE tissues. In order t...
ORGANISM(S): Homo sapiens 
2011-09-05 | E-TABM-1081 | biostudies-arrayexpress
GenomicsFresh versus slow-frozen ATACseq samples for salmon tissues
Fresh versus slow-frozen ATACseq samples for salmon tissues
PRJEB38052 | ENA
MetabolomicsDESI mass spectrometry imaging of murine tissues

DESI-MS imaging results of a murine colorectal tumour tissue, a murine jejunum tissue and a Helicobacter pylori-infected murine stomach tissue are available. Data were all obtained under negative ion mode. Corresponding H&E staining results can be found in the associated publication

2025-07-10 | MTBLS10846 | MetaboLights
TranscriptomicsTranscription profiling of fresh, frozen and RNALater preserved human uterine myometrium samples
We used quantitative RNA expression profiling on the Affymetrix U133 human expression array to validate quantitative expression results obtained with the tissue preservative RNALater against snap frozen and fresh tissues as a means of routine tissue collection and temporary storage. By using split ...
ORGANISM(S): Homo sapiens 
2007-06-21 | E-GEOD-1296 | biostudies-arrayexpress
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9794 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9795 | MetaboLights
ProteomicsComparison of FFPE and fresh frozen prostate tissues using PCT SWATH
We compared the proteomes of FFPE and fresh frozen tissues (both tumorous and non-tumorous) from 16 prostate cancer patients using pressure cycling technology and SWATH-MS.
ORGANISM(S): Homo sapiens (Human) 
2019-10-07 | PXD004691 | Pride
Prostate cancer  pct-swath  ffpe 
ProteomicsExtracellular vesicles isolated from fresh vs frozen melanoma tissues are similar in purity, protein composition, and tumor antigenicity
Extracellular vesicles (EVs) are nano-sized particles released by cells, enriched in disease-related molecules, gaining attention as potential tumor biomarkers and useful tools for cancer immunotherapy. Tumor tissues are valuable sources of EVs, reflecting the tumor's molecular profile. This study i...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD068552 | Pride
Tmt Extracellular vesicles Melanoma Isolation Global quantitative proteomics 
TranscriptomicsAn array based analysis of miRNA expression comparing matched frozen and FFPE human tissue samples
MicroRNAs (miRNAs) are small non-coding RNAs that repress gene expression at the post transcriptional level via an antisense RNA-RNA interaction. Generally, miRNAs derived from snap frozen or fresh samples are used for array based profiling. Since tissues in most pathology departments are available ...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-12458 | biostudies-arrayexpress
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