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TranscriptomicsTranscription profiling of mouse frontal cortex after treatment with zntipsychotic drugs
Antipsychotic drugs are classified as typical and atypical based on extrapyramidal effects. However, since the frontal cortex is one of the most important regions for antipsychotic actions, this study attempted to classify antipsychotic drugs based on gene expression in the frontal cortex. Chlorprom...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-1501 | biostudies-arrayexpress
ProteomicsHuman fetal left and right frontal lobes LC-MSMS
Inherent hemispheric asymmetry is significant for cognition, language and other functions. An understanding of normal brain and asymmetry development in the early period will further the knowledge of how different hemispheres prioritize specific functions, which is still unknown. We analysed the dev...
ORGANISM(S): Homo sapiens (Human) 
2022-09-30 | PXD034192 | Pride
Fetal frontal lobe 
TranscriptomicsTranscription profiling of response of Rattus norvegicus frontal cortex to chronic olanzapine treatment
Male Sprague-Dawley albino rats (Charles River) initially weighting approximately 200 grams were randomly assigned to one of the following: 1) olanzapine (2 mg/kg/day, I.P.) (N=20) or 2) Saline (N=20) and administered olanzapine or saline for 21 days. Frontal cortex (N=4/group) was dissected and ho...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2547 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human frontal cortices from individuals with Retts syndrome
Four sets of six microarray experiments were conducted. Six individual RTT frontal cortices were co-hybridized with six individual control frontal cortices. For example, the frontal cortex of patient RTT1 was compared with the occipital cortex of RTT1. Additionally, where the frontal cortex of a RTT...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-MEXP-2588 | biostudies-arrayexpress
TranscriptomicsMicroarrays of frontal cortex (area 8) of Parkinson cases and controls
Microarrays of frontal cortex (area 8) of Parkinson cases and controls
ORGANISM(S): Homo sapiens 
2013-06-02 | E-MTAB-1194 | biostudies-arrayexpress
GenomicsRiMod Methylation frontal
Illumina EPIC methylation array of frontal lobe tissue from post-mortem human brains of the RiMod-FTD project
EGAD00010002055 | EGA
TranscriptomicsAnalysis of gene expression profiling of normal retina and brain cortices
Using a canine custom retinal cDNA microarray our aim is to identify normal gene expression profiling for retina and frontal, occipital and temporal brain cortices Total RNA was isolated using Trizol reagent (Invitrogen, Carlsbad, CA) and further purified by Rneasy mini kit (Qiagen, Valencia, CA). P...
ORGANISM(S): Canis familiaris 
2010-07-01 | E-GEOD-5208 | biostudies-arrayexpress
TranscriptomicsFrontal Cortex Transcriptome Analysis of Mice Exposed to Electronic Cigarettes During Early Life Stages
Our study demonstrated that e-cigarettes, both with and without nicotine, induced sex-dependent gene expression change. This RNA-seq study examined the expression profiles of brain frontal cortex samples from mice exposed to classic tobacco flavored bluâ„¢ e-cigarettes during gestation and lactation...
ORGANISM(S): Mus musculus 
2016-02-01 | E-GEOD-75858 | biostudies-arrayexpress
TranscriptomicsFrontal lobe (brain) Illumina Inf 450 DNA methylation samples from HIV+ and HIV- human subjects
Genome wide DNA methylation profiles of Frontal Lobe from HIV positive and HIV negative human subjects. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 486,000 CpGs. Dataset included 33 subjects from the USA. The epigen...
ORGANISM(S): Homo sapiens 
2015-06-09 | E-GEOD-67749 | biostudies-arrayexpress
TranscriptomicsMethylation state of human post-mortem brain tissue from the frontal lobe of patients with Frontotemporal Dementia and healthy controls
Methylation state of human post-mortem brain tissue from the frontal lobe of patients with Frontotemporal Dementia caused by mutations in GRN, MAPT and C9orf72 and healthy controls
ORGANISM(S): Homo sapiens 
2023-02-01 | E-MTAB-12674 | biostudies-arrayexpress
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