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TranscriptomicsGene-expression profiles after siRNA knockdown and overexpression of bromodomian containing 1 (BRD1) in HEK293T cells
Background: The bromodomain containing 1 (BRD1) gene has been implicated with transcriptional regulation, brain development and susceptibility to schizophrenia and bipolar disorder. Results: To advance the understanding of BRD1 and its role in mental disorders, we characterized the protein and chrom...
ORGANISM(S): Homo sapiens 
2016-03-16 | E-GEOD-79255 | biostudies-arrayexpress
GenomicsIdentification of the BRD1 interactome and its impact on schizophrenia risk
We identified protein-protein interactions and chromatin binding sites for two isforms of BRD1 (BRD1-S and BRD1-L) using Co-IP MS/MS and ChIP-seq. BRD1 isoforms were cloned, epitope-tagged (pcDNA 6 V5-His6, Lifetechnologies) and stably expressed in HEK293T cells. Chromatin immunoprecipitations were ...
ORGANISM(S): Homo sapiens 
2015-10-29 | E-GEOD-62811 | biostudies-arrayexpress
UnknownEWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions.
Not available
S-EPMC4647676 | biostudies-literature
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