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MetabolomicsNano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis

Many patients are suffering from atherosclerosis without typical risk factors, which can cause severe cardiovascular complications. Trimethylamine N-oxide (TMAO), derived from gut microbes, is a key unconventional contributor to the development of atherosclerosis. Here we present a stra...

2025-10-25 | MTBLS12426 | MetaboLights
ProteomicsOTUD7B promotes cardiac hypertrophy by deubiquitinating SERCA2a
Cell samples were lysed in lysis buffer (8 M urea, 1% protease inhibitor cocktail). The supernatant was collected and the protein concentration was determined with BCA kit according to the manufacturer’s instructions. The peptides were obtained by digesting the protein with trypsin. Then, peptides w...
ORGANISM(S): Rattus Norvegicus 
2025-09-27 | PXD068918 |
ProteomicsIP-MS of NRVMs overexpressing Asb10
To find out the potential interacting proteins of Asb10 in cardiomyocytes, we conducted the IP-MS in NRVMs overexpressing Asb10.
ORGANISM(S): Rattus Norvegicus 
2025-03-07 | PXD061568 |
ProteomicsProteome of patient-derived iPSC-CMs with LMNA mutation
Tandem Mass Tag-Based proteomic analysis was performed to detect protein expression changes between gene correction and LMNA mutation iPSC-CMs
ORGANISM(S): Homo Sapiens 
2023-01-15 | PXD039452 |
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