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ProteomicsSolvent-Induced partial Cellular Fixation Approach enables systematic identification of drug targets and temporal progression of downstream biochemical pathways in living cells
In this study, we introduce a novel approach, the Solvent-Induced Partial Cellular Fixation Approach (SICFA), to monitor drug targets and the temporal progression of downstream biochemical pathways in living cells. We observed that proteins in living cells undergo unfolding and aggregation when expo...
ORGANISM(S): Homo sapiens (Human) 
2025-10-15 | PXD057157 | Pride
Proteomics  protein stability  drug target identification  drug binding potency  downstream effector proteins  living cells analysis 
MetabolomicsMetabonomic analysis of human and 12 kinds of livestock mature milk

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
ProteomicsProteome data from an external validation cohort using MRM-MS targeted proteomics assay
These are raw mass spectrometry files obtained by MRM from the external validation cohort, used to validate findings from the Guangzhou Nutrition and Health Study.
ORGANISM(S): Homo Sapiens 
2024-10-18 | PXD056935 |
ProteomicsCirculating proteome profiling of Guangzhou Nutrition and Health Study
Guangzhou Nutrition and Health Study was a community-based cohort study in Guangzhou, China.
ORGANISM(S): Homo Sapiens 
2023-01-03 | PXD039231 |
ProteomicsCirculating proteome profiling of Westlake Precision Birth Cohort
Westlake Precision Birth Cohort (WEBIRTH) consists of gestational women living in Hangzhou, China.
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD038253 |
ProteomicsGNHS proteome SWATH data datatat
Here, we explored the feasibility to use a protein-based machine learning model for risk prediction of MetS in a prospective cohort.
ORGANISM(S): Homo Sapiens 
2023-03-11 | PXD039236 |
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