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Epithelia of small and large intestines differ in their structures and functions. Such heterogeneity between these two epithelial tissues might be controlled by both epithelium-intrinsic and -extrinsic programs. By employing the cell transplantation technique developed in our laboratory, we investig...
ORGANISM(S): Mus musculus 
Idiopathic pulmonary fibrosis is a chronic devastating disease of unknown etiology. No therapy is currently available. A growing body of evidence supports the role of TGFβ1 as the major player in the pathogenesis of the disease. This study designed novel human- and mouse-specific siRNAs and siRNA/DN...
ORGANISM(S): Mus musculus 
In this prospective study, we analyzed stool proteomes from four patients with well-controlled conditions, four patients with recurrent cholangitis, and three patients with prolonged jaundice but no cholangitis, all of whom had undergone Kasai portoenterostomy for biliary atresia (BA). The study als...
ORGANISM(S): Homo Sapiens (human) 
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