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MetabolomicsPrevotella vs. Ruminococcus enterotypes drive divergent milk fat synthesis in dairy cows through rumen microbiota-host metabolic crosstalk

Background: High-yield dairy cows are usually accompanied with lower milk fat (MF) rate, with huge variations in MF contents among individuals. The potential mechanisms of key microorganisms, their genes and metabolites participate in MF synthesis are still not well understood. By selec...

2025-10-28 | MTBLS13211 | MetaboLights
TranscriptomicsThe impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. (COPRO-Seq)
Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans, and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we ...
ORGANISM(S): Bacteria 
2011-11-01 | E-GEOD-31943 | biostudies-arrayexpress
Proteomicsmilk-derived extracellular vesicles UHPLC-MS
Breast milk contains macromolecular components with distinctive functions, whereby milk fat globules and casein micelles provide nutrition, while whey contains molecules that stimulate the infant’s immunity. Interestingly, the importance and function of extracellular vesicles (EV) in milk has not be...
ORGANISM(S): Homo sapiens (Human) 
2016-09-27 | PXD004423 | Pride
Lc-ms Human milk Vesicles Milk proteome 
MetabolomicsThe stability and functional redundancy of a microbial cheese ecosystem subjected to a biotic perturbation
The cheese microbial community is dense with relatively low complexity and composed of cultivable prokaryotic and eukaryotic microorganisms. The ripening process can thus be reproduced under controlled conditions. A reduced microbial community composed of yeasts and bacteria was assembled to mimic t...
2024-04-29 | MTBLS6968 | MetaboLights
ProteomicsKefir peptide profiling - Peptidomic analysis reveals proteolytic activity of kefir microorganisms on bovine milk proteins
This study examines the proteolytic activity of the kefir grains (a combination of bacteria and yeast) on bovine milk proteins. SDS-PAGE analysis reveals substantial digestion of milk proteins by the kefir grains in comparison with control samples. Mass spectrometric analysis reveals that the kefir ...
ORGANISM(S): Bos taurus (Bovine) 
2016-05-09 | PXD001826 | Pride
Kefir Peptide Protein Peptidomic Milk 
MetabolomicsMetabolic programming and functional remodeling by a c-di-GMP-centric hierarchy in aerobic granular sludge

This study systematically elucidates the hierarchical signaling regulatory network in aerobic granular sludge (AGS) by integrating dynamic analysis of quorum sensing signal molecules, microbial community structure profiling, and metabolomic characterization. The research reveals that c-di-GMP fun...

2025-12-10 | MTBLS13486 | MetaboLights
UnknownImprovement of Quality of Sour Camel Milk by Extract of <i>Sparassis crispa</i>: Physicochemical Properties, Sensory Quality and Metabolic Changes.
Not available
S-EPMC12428353 | biostudies-literature
TranscriptomicsElevated dairy fat intake in lactating women alters milk lipid and fatty acids without detectible changes in expression of genes related to lipid uptake or synthesis
Previous work has demonstrated that elevated maternal lipid intake (particularly from dairy products) is associated with increased lipids and altered fatty acid profile in milk produced by healthy lactating women. We investigate our primary hypothesis that a maternal diet rich in full-fat dairy prod...
ORGANISM(S): Homo sapiens 
2015-02-24 | E-GEOD-66191 | biostudies-arrayexpress
ProteomicsPhosphoproteomics of the Milk Fat Globule Membrane: new insights into lipid droplet secretion from the mammary epithelial cell
Lipid droplets are secreted into milk by a complex process which begins by burgeoning oflipids at the endoplasmic reticulum of the mammary epithelial cell (MEC). Lipid dropletsenveloped by organelle-derived phospholipids reach the apical pole of the cell where they arewrapped by t...
ORGANISM(S): Capra hircus (Goat) 
2015-05-12 | PXD001039 | Pride
Mammary epithelial cell Secretion Phosphoproteome Milk Lipid droplet 
TranscriptomicsTranscription profiling by array of human blood in dairly product consumption time series.
With the aim of investigating the genome-wide postprandial effects of single servings ingestion of milk and yogurt on gene expression in the blood cells of human subjects and to identify the downstream physiological processes regulated by the differentially expressed genes we conducted a randomized,...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-MEXP-2571 | biostudies-arrayexpress
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