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MetabolomicsA novel micro-voltage driven fungal system for simultaneous removal of microplastics, antibiotics, and heavy metals

Microplastics, antibiotics, and heavy metals are co-occurring pollutants in wastewater, posing significant environmental risks and potential threats to human health. However, there is currently no effective wastewater treatment method for this type of combined pollution. This study establishes a ...

2026-01-05 | MTBLS13609 | MetaboLights
MetabolomicsInsights into Metabolic Changes Caused by the Trichoderma virens-Maize Root Interaction
The interactions of crops with root-colonizing endophytic microorganisms are highly relevant to agriculture, because endophytes can modify plant resistance to pests and increase crop yields. We investigated the interactions between the host plant Zea mays and the endophytic fungus Trichode...
2021-07-08 | MTBLS1964 | MetaboLights
MetabolomicsDeletion of Gliotoxin Biosynthesis Remodels the Intra- and Extracellular Metabolic Status of Aspergillus fumigatus, Alters Its Virulence-Related Phenotypes, and Modulates Host Immune Responses_Mycelium

Gliotoxin is a secondary metabolite produced by Aspergillus fumigatus, known to play a significant role in immune regulation and virulence phenotypes. This study investigates how the deletion of gliotoxin biosynthesis remodels the metabolic state of A. fumigatus and subsequently af...

2026-05-11 | MTBLS14012 | MetaboLights
MetabolomicsDeletion of Gliotoxin Biosynthesis Remodels the Intra- and Extracellular Metabolic Status of Aspergillus fumigatus, Alters Its Virulence-Related Phenotypes, and Modulates Host Immune Responses_culture supernatant

Gliotoxin is a secondary metabolite produced by Aspergillus fumigatus, known to play a significant role in immune regulation and virulence phenotypes. This study investigates how the deletion of gliotoxin biosynthesis remodels the metabolic state of A. fumigatus and subsequently af...

2026-05-11 | MTBLS14011 | MetaboLights
ProteomicsComparative genomics reveals high biological diversity and specific adaptations in the fungal genus Aspergillus
The project compares the genomes of multiple Aspergillus species. In particular, the genes involved in the degradation of plant-derived biomass have been analyzed. As well, the extracellular proteins produced by the fungi during the utilization of sugar beet pulp and wheat bran were examined by LC-M...
ORGANISM(S): Aspergillus wentii Aspergillus zonatus Aspergillus aculeatus ATCC 16872 Aspergillus tubingensis Aspergillus carbonarius ITEM 5010 Aspergillus versicolor Aspergillus foetidus var. acidus Aspergillus brasiliensis Aspergillus sydowii 
2018-10-26 | PXD005563 | Pride
Extracellular proteins Biomass degradation Aspergilli Lc-ms/ms 
ProteomicsCoordination of fungal biofilm development by extracellular vesicle cargo
The fungal pathogen Candida albicans can form biofilms that protect it from drugs and the immune system. The biofilm cells release extracellular vesicles (EVs) that promote extracellular matrix formation and resistance to antifungal drugs. Here, we define functions for numerous EV cargo proteins in ...
ORGANISM(S): Candida albicans (Yeast) 
2022-02-16 | PXD028596 | Pride
Candida albicans Extracellular vesicles Matrix proteomics Biofilm Biofilms 
ProteomicsFungal extracellular vesicles are recoverable across variable ultracentrifugation speeds but display species-specific profiles of sedimentation
Extracellular vesicles (EVs) are central components of fungal biology, yet their isolation commonly relies on ultracentrifugation schemes originally developed for mammalian systems. In Cryptococcus, most EVs carry the capsular polysaccharide glucuronoxylomannan (GXM), raising the possibility that ve...
ORGANISM(S): Cryptococcus neoformans RCT29 
2026-06-29 | PXD076414 | Pride
Fungal extracellular  vesicles  ultracentrifugation  profiles 
TranscriptomicsTranscriptome data for bacterial and fungal keratitis compared to cadaver cornea
Microbial keratitis is a major cause of blindness worldwide. An excessive host inflammatory response can occur even after adequate antimicrobial treatment. This results in tissue damage with corneal thinning and even perforation, which may require corneal transplantation. In this study we investigat...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-GEOD-58291 | biostudies-arrayexpress
ProteomicsVesicle proteomics during fungal biofilm development in Candida
Proteomic profiling of extracellular vesicles from four different Candida strains (tropicalis, parapsilosis, auris and glabrata).
ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata) [Candida] auris Candida parapsilosis Candida tropicalis (Yeast) 
2022-10-14 | PXD035068 | Pride
Extracellular vesicles Candida Biofilm Lc-ms/ms 
GenomicsPlant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection
Plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection
PRJNA808784 | ENA
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