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MetabolomicsTrcrtB regulates carotenoids biosynthesis, stress tolerance, conidiation and pathogenicity in the postharvest pink rot fungus, Trichothecium roseum

Trichothecium roseum is a highly destructive postharvest pathogenic fungus that causes pink mold rot in various fruits and leads to significant agricultural and economic losses. While Phytoene is known to be crucial for phytopathogens, its roles in postharvest fungi, remain largely obsc...

2026-07-22 | MTBLS15120 | MetaboLights
MetabolomicsFungus Rhizopus microsporus var. rhizopodiformis Promotes Hepatic Steatosis via Upregulation of Hepatic Neutrophil Degranulation

Objective:

Metabolic associated fatty liver disease (MAFLD) affects approximately 25% of the global population, posing a serious threat to public health, and its pathogenesis remains largely unknown. Gut fungi play a significant role in the development of liver diseases, but the gut microbi...

2025-12-01 | MTBLS13120 | MetaboLights
MetabolomicsFungus Rhizopus microsporus var. rhizopodiformis Promotes Hepatic Steatosis via Upregulation of Hepatic Neutrophil Degranulation

Objective:

Metabolic associated fatty liver disease (MAFLD) affects approximately 25% of the global population, posing a serious threat to public health, and its pathogenesis remains largely unknown. Gut fungi play a significant role in the development of liver diseases, but the gut microbi...

2026-01-17 | MTBLS13705 | MetaboLights
MetabolomicsThe murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria
Here, we report significant changes in the composition of the lung microbiome and metabolome of mice under immune suppression, infection of immunosuppressed mice with virulent and avirulent strains of the clinically important human-pathogenic fungus Aspergillus fumigatus, and treatment with the clin...
2025-07-04 | MTBLS12262 | MetaboLights
MetabolomicsCascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
MetabolomicsMetabolic alterations in pea leaves during arbuscular mycorrhiza development

Arbuscular mycorrhiza (AM) is known to be a mutually beneficial plant-fungal symbiosis; however, the effect of mycorrhization is heavily dependent on multiple biotic and abiotic factors. Therefore, for the proper employment of such plant-fungal symbiotic systems in agriculture, a detailed underst...

2020-02-09 | MTBLS893 | MetaboLights
TranscriptomicsComparison of transcript abundance in mycelium from the rice blast fungus Magnaporthe oryzae grown in rich medium and in minimal medium using RNA-Seq
Mycelium from the rice blast fungus Magnaporthe oryzae was grown in both rich medium and under nutrient limiting conditions. Genes were identified that were more highly expressed in one condition as compared to the other. Samples were taken from mycelium grown in both complete medium and in glucose ...
ORGANISM(S): Magnaporthe oryzae 
2012-02-13 | E-GEOD-30327 | biostudies-arrayexpress
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
TranscriptomicsDevelopmental transcriptomics of the model caterpillar fungus Cordyceps militaris
The RNA-Seq technique was used to investigate the differentially transcribed genes of the caterpillar fungus Cordyces militaris. It was calculated that >63% of total annotated genes were expressed, including >55% of putative pathogen-host interaction genes. Overall, the fruiting-body development and...
ORGANISM(S): Cordyceps militaris 
2011-11-08 | E-GEOD-28001 | biostudies-arrayexpress
TranscriptomicsComparison of transcript abundance in mycelium from the rice blast fungus Magnaporthe oryzae grown in rich medium and in minimal medium using HT-SuperSAGE.
Mycelium from the rice blast fungus Magnaporthe oryzae was grown in both rich medium and under nutrient limiting conditions. Genes were identified that were more highly expressed in one condition as compared to the other. Samples were taken from mycelium grown in both complete medium and in glucose...
ORGANISM(S): Magnaporthe oryzae 
2012-02-13 | E-GEOD-30256 | biostudies-arrayexpress
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