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ProteomicsLongitudinal Serum Proteomics in Hypertensive Kidney Disease Progression
Hypertensive nephrosclerosis (HN) is a major cause of end-stage renal disease (ESRD), however, longitudinal studies employing serum proteomics to document its progression are few. This study aims to identify potential circulating biomarkers indicative of disease progression in HN by performing serum...
ORGANISM(S): Homo sapiens (Human) 
2025-11-21 | PXD055241 | Pride
Serum 
ProteomicsProteome of renal tubuli and serum differentiate pre-existing type 2 diabetes and post-transplant diabetes in kidney transplant recipients
This study explores these differences by comparing the proteomes of proximal tubules and serum from normoglycemic (NG), pre-transplant T2DM, and PTDM patients one-year post-kidney transplantation.
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD054961 | Pride
Serum 
ProteomicsMitochondrial stress in GLA mutants Zebrafish is independent of globotriaosylceramide accumulation
Fabry disease (FD) is a hereditary lysosomal storage disorder caused by mutations in GLA gene resulting in reduction or lack of α-galactosidase A activity. In humans, enzymatic deficiency leads to accumulation of globotriaosylceramide (Gb3) and other glycosphingolipids in lysosomes. Current therapie...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-10-24 | PXD035409 | Pride
Alpha-galactosidase a/ fabry disease/ lysosome/ mitochondrial activity/ proteomic approach 
ProteomicsProteome of renal tubuli and serum differentiate pre-existing type 2 diabetes and post-transplant diabetes in kidney transplant recipients
This study explores these differences by comparing the proteomes of proximal tubules and serum from normoglycemic (NG), pre-transplant T2DM, and PTDM patients one-year post-kidney transplantation.
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD054937 | Pride
Transplant Ptdm Tubuli 
ProteomicsPost-transplant diabetes mellitus after kidney transplantation
Diabetes mellitus (DM) after transplantation remains a crucial clinical problem in kidney transplantation. To obtain insights into molecular mechanisms underlying the development of post-transplant diabetes mellitus (PTDM) and its early impact on glomerular structures, here we comparatively analyze...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042188 | Pride
Human Ptdm. t2dm Kidney Tranplantation 
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