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TranscriptomicsIdentification of potential miR-31 target-genes in Ewing Sarcoma
We identified miR-31 as strongest downregulated miRNA in the bone tumor Ewing sarcoma. To identify miR-31 targets in ES genome-wide gene expression profiles of TC71 cells transfected with miR-31 mimics or negative control (Life Technologies) generated in three independent experiments (a, b, c). Tota...
ORGANISM(S): Homo sapiens 
2012-10-23 | E-MTAB-1334 | biostudies-arrayexpress
GenomicsFused in sarcoma regulates DNA replication timing and progression
Fused in sarcoma regulates DNA replication timing and progression
PRJNA616354 | ENA
ProteomicsFused in sarcoma regulates DNA replication timing and progression
Fused-in-sarcoma (FUS) encodes an RNA-binding protein with diverse roles in transcriptional activation and RNA splicing. While oncogenic fusions of FUS and transcription factor DNA-binding domains are associated with soft tissue sarcomas, dominant mutations in FUS cause amyotrophic lateral sclerosi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-24 | MSV000087698 | MassIVE
ProteomicsDiscovery-Based Protein Expression Profiling Identifies Distinct Subgroups and Pathways in Leiomyosarcomas
20 tumor samples run in duplicates, consisting of pleomorphic sarcomas; classfied as leiomyosarcoma or high-grade undifferentiated pleomorphic sarcoma.
ORGANISM(S): Homo sapiens (Human) 
2020-01-27 | PXD000616 | Pride
Sarcoma human label-free 
TranscriptomicsmiRNA expression profiles from Ewing sarcoma samples, Ewing sarcoma cell lines and mesenchymal stem cells
For the identification of differentially expressed miRNA relevant for ES pathogenesis and clinical behaviour miRNA expression profiling of 377 miRNAs for 40 fresh-frozen ES samples, including primary cases and metastases and cases with different translocation types and 6 ES cell lines and compared t...
ORGANISM(S): Homo sapiens 
2012-10-23 | E-MTAB-1337 | biostudies-arrayexpress
GenomicsTargeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [CLIP-Seq]
Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [CLIP-Seq]
PRJNA1366401 | ENA
GenomicsTargeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [RNA-Seq PCLS]
Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [RNA-Seq PCLS]
PRJNA1366403 | ENA
GenomicsTargeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [RNA-Seq IPF]
Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [RNA-Seq IPF]
PRJNA1366400 | ENA
GenomicsTargeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis
Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis
PRJNA1366387 | ENA
TranscriptomicsAltered Distributions of SMN-containing GEMs and Mitochondria in Motor Neurons of TDP-43 transgenic Mice
TDP-43, a DNA/RNA binding protein involved in RNA transcription and splicing has been associated with the pathophysiology of neurodegenerative diseases, including ALS. However, the function of TDP-43 in motor neurons remains undefined. Here, we employ both gain- and loss-of-function approaches to de...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-22351 | biostudies-arrayexpress
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