Fusion partner - OmicsDI

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Unknown (782)
Proteomics (162)
Genomics (157)
Transcriptomics (113)
Other (9)
Methylation profiling (2)
Metabolomics (2)

Organisms

Allexis (142)
Arabidopsis thaliana (142)
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Callinectes sapidus (142)
Drosophila melanogaster (142)
Entamoeba histolytica HM-1:IMSS-A (142)
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Homo sapiens (142)
Leishmania major strain Friedlin (142)
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Medicago truncatula (142)
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Methylohalobius crimeensis 10Ki (142)
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Mus musculus (37)
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Organisms

Homo sapiens (67)
Mus musculus (30)
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Drosophila melanogaster (1)
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Repository

pride (142)
ENA (123)
geo (92)
biostudies-arrayexpress (56)
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Jump-In-T-REx HEK293 cell (1)

Disease

Breast cancer (7)
Disease free (5)
Acute leukemia (4)
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Not Available (1)
Alzheimer's disease (1)
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Plasmodium falciparum malaria (1)
Prostate adenocarcinoma (1)
Trypanosomiasis (1)

Technology Type

Mass Spectrometry (142)
Shotgun proteomics (66)
Affinity purification coupled with mass spectrometry proteomics (43)
Bottom-up proteomics (32)
Data-dependent acquisition (18)
Data-independent acquisition (8)
Gel-based experiment (6)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
Top-down proteomics (3)
Mass spectrometry (2)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiScanSQ, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Affinity proteomics (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Orbitrap Fusion Lumos (4)
LTQ Orbitrap Elite (3)
Affymetrix Fluidics Station (1)
Illumina NovaSeq X (1)
NextSeq 2000 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Instrument (1)
LCQ Deca XP Plus (1)
Orbitrap Fusion (1)
Orbitrap Fusion ETD (1)
Q Exactive (1)
Q Exactive HF (1)
Q Exactive Plus (1)
TimsTOF (1)
Liquid Chromatography MS - alternating (1)
Flow injection analysis MS - negative (1)
Flow injection analysis MS - positive (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2026 (49)
2025 (40)
2024 (36)
2022 (29)
2023 (24)
2021 (24)
2020 (20)
2018 (14)
2014 (13)
2017 (10)
2016 (10)
2015 (10)
2008 (6)
2013 (5)
2010 (4)
2011 (3)
2005 (3)
2019 (3)
2012 (2)
2009 (2)
2007 (2)

CHEBI ID

CHEBI:26271 (2)
CHEBI:18186 (2)
CHEBI:30887 (2)
CHEBI:17750 (2)
CHEBI:28842 (2)
CHEBI:16015 (2)
CHEBI:17858 (2)
CHEBI:16347 (2)
CHEBI:15354 (2)
CHEBI:16643 (2)
CHEBI:17295 (2)
CHEBI:17596 (2)
CHEBI:28716 (2)
CHEBI:15756 (2)
CHEBI:16828 (2)
CHEBI:17368 (2)
CHEBI:62194 (1)
CHEBI:139108 (1)
CHEBI:61425 (1)
CHEBI:48681 (1)
CHEBI:27537 (1)
CHEBI:28935 (1)
CHEBI:24549 (1)
CHEBI:28599 (1)
CHEBI:104362 (1)
CHEBI:104012 (1)
CHEBI:61958 (1)
CHEBI:42465 (1)
CHEBI:71316 (1)
CHEBI:62012 (1)

Metabolite Name

Choline (2)
L-Tryptophan (2)
L-Carnitine (2)
L-Methionine (2)
Inosine (2)
Hypoxanthine (2)
D-carnitinyl-CoA (1)
Crotonobetainyl-CoA (1)
Adenosine thiamine triphosphate (1)
6-hydroxymethyl-dihydropterin pyrophosphate (1)
Hexadecanoyl-phosphate (n-C16:0) (1)
Psicoselysine (1)
Ferric 2,3-dihydroxybenzoylserine (1)
Dihydromonapterin (1)
Tetradecenoate (n-C14:1) (1)
L-alanine-L-glutamate (1)
L-alanine-D-glutamate (1)
Cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (1)
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (1)
5'-deoxyribose (1)
Octanoate (protein bound) (1)
3-Aminoacrylate (1)
Cyclic pyranopterin monophosphate (1)
L-ascorbate-6-phosphate (1)
Dehydroglycine (1)
Gamma-glutamyl-gamma aminobutyric acid (1)
3-keto-L-gulonate-6-phosphate (1)
2,3-dihydroxycinnamic acid (1)
Cis-3-(3-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol (1)
3-(3-hydroxy-phenyl)propionate (1)

First Public Date

2026 (31)
2024 (19)
2025 (16)
2014 (10)
2023 (8)
2021 (8)
2022 (7)
2018 (7)
2017 (7)
2020 (3)
2013 (3)
2016 (2)
2019 (1)
2015 (1)

Modification

1x(15)N labeled L-valine (1)
4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (30)
RNA-seq of coding RNA (10)
ChIP-seq (4)
ChIP-chip by tiling array (2)
Comparative genomic hybridization by array (2)
Transcription profiling by SAGE (1)
Unknown experiment type (1)
RNAi profiling by array (1)
Genotyping by array (1)
Other (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2022 (75)
2023 (68)
2021 (63)
2025 (54)
2019 (52)
2016 (50)
2020 (50)
2018 (48)
2015 (44)
2024 (42)
2013 (41)
2014 (39)
2017 (37)
2012 (27)
2011 (26)
2008 (19)
2010 (13)
2007 (13)
2026 (11)
2006 (11)
2009 (10)
2005 (10)
2000 (8)
2003 (6)
1998 (6)
2001 (4)
1999 (4)
1997 (3)
2004 (2)
2002 (2)

Lab affiliation

German Cancer Consortium (DKTK), partner site Freiburg German Cancer Research Center (DKFZ) Foundation under Public Law c/o Department of Urology Zentrale Klinische Forschung (ZKF) Medical Center-University of Freiburg Breisacher Str. 66, 79106 Freiburg, Germany (4)
Department of Biology, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany (3)
School of Biosciences, University of Sheffield, Sheffield, UK (3)
Chair of Proteomics and Bioanalytics Technische Universitaet Muenchen Partner Site of the German Cancer Consortium Emil Erlenmeyer Forum 5 85354 Freising Germany (2)
Department of Biochemistry, University of Regina, Regina, Saskatchewan S4S 0A2, Canada. (2)
Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, CH-1211 Switzerland (2)
EDyP (2)
Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (2)
Head of the Curie Institute Mass Spectrometry Platform (2)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany Frankfurt Cancer Institute, Frankfurt am Main, Germany Cardio-Pulmonary Institute, Frankfurt am Main, Germany (2)
University of Edinburgh (2)
University of Oxford (2)
1 Molecular Proteomics Laboratory, Biological Medical Research Center, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany 2 Institute for Molecular Medicine, Proteome Research, University Hospital and Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (1)
1 Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada 2 Department of Molecular Genetics, University of Toronto, Toronto, ON M5S1A5, Canada (1)
1) Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France 2) Infrastructure nationale de protéomique, ProFI, FR 2048, Toulouse, France (1)
1. Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany 2. Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH93BF, United Kingdom (1)
1. German Cancer Consortium (DKTK) partner site Freiburg, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany 2. Department of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany (1)
1Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. 2Analytical Instrumentation Center, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. 3Center for Quantitative Biology, PKU-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China (1)
1Department of Parasitology, Faculty of Science, Charles University, BIOCEV, Průmyslová 595, 25250 Vestec, Czech Republic (1)
1Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 5Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 8Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA (1)
1VIB-UGent Center for Medical Biotechnology, VIB, 9052 Ghent, Belgium 2Department of Biomolecular Medicine, Ghent University, 9052 Ghent, Belgium (1)
Apoptosis and Molecular Disease Lab, Department of Biological Sciences, Seoul National University (1)
Associate Professor, Department of Biochemistry & Molecular Biology, UTMB Mass Spectrometry Director, University of Texas Medical Branch – Galveston, Texas, USA (1)
Baylor College of Medicine (1)
Biomedical Center, LMU Munich Molecular Biology Großhaderner Strasse 9 82152 Planegg-Martinsried Phone: (089) 2180 75420 (1)
Biomedical Research Institute of New Jersey (BRInj) 140 East Hanover Ave Cedar Knolls New Jersey 07927 (1)
CRUK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. (1)
CSIRO Biomedical Manufacturing Biology R&D Group (1)
CSIRO Biomedical Manufacturing Protein Mass Spectrometry Lab Parkville, VIC 3052, Australia (1)

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Fusion partner directed chromatin occupancy drives the transcriptome heterogeneity of MLL-fusion acute lymphoblastic leukemia

PRJNA407757 | ENA

Partner-independent fusion gene detection by multiplexed CRISPR/Cas9 enrichment and long-read Nanopore sequencing

Fusion genes are hallmarks of various cancer types and important determinants for diagnosis, prognosis and treatment possibilities. The promiscuity of fusion genes with respect to partner choice and exact breakpoint-positions restricts their detection in the diagnostic setting, even for known and re...

EGAS00001003964 | EGA

AGAP3: a novel BRAF-fusion partner in pediatric pancreatic acinar cell carcinoma

PRJNA838965 | ENA

Menin-MLL inhibitors block oncogenic transformation by MLL fusion proteins in a fusion partner independent manner

Chromosomal rearrangements of the Mixed Lineage Leukemia (MLL) gene result in fusion proteins which retain the N-terminal portion of MLL fused with one of more than 70 different fusion partners. The high diversity of MLL fusion partners raises a question whether it is possible to develop a general t...

ORGANISM(S): Mus musculus

2018-06-09 | GSE69740 | GEO

Fusion partners influence cellular and molecular phenotypes of oncogenic BRAF fusions

Fusion genes can be oncogenic drivers in a variety of cancer types and represent potential targets for targeted therapy. The BRAF gene is frequently involved in oncogenic fusions, with fusion frequencies of 0.2-3% throughout different cancers. However, BRAF fusions rarely occur in the same gene conf...

ORGANISM(S): Homo sapiens (Human)

2020-01-16 | PXD013461 | Pride

Fusion partner directed chromatin occupancy drives the transcriptome heterogeneity of MLL-fusion acute lymphoblastic leukemia

Fusion of the N-terminus of the mixed-lineage-leukemia (MLL) gene with various partner genes drives acute lymphoblastic leukemia (ALL). Despite the fusion proteins sharing some common attributes, transcriptome heterogeneity of MLL-fusion ALL is observed and the underlying mechanism and biological co...

ORGANISM(S): Homo sapiens

2018-04-30 | GSE103947 | GEO

NSD3-NUT Fusion Oncoprotein in NUT Midline Carcinoma identified in 1221 patient-derived cell line by RNA-seq

Discarded live tumor tissue from a metastatic focus in the patientM-bM-^@M-^Ys lung was collected under institutional review board approval through the NUT midline carcinoma registry (www.NMCRegistry.org). From this tissue the first known NUT-variant cell line, 1221, was established. To determine th...

ORGANISM(S): Homo sapiens

2014-08-01 | E-GEOD-57222 | biostudies-arrayexpress

Mus musculus

Menin-MLL inhibitors block oncogenic transformation by MLL fusion proteins in a fusion partner independent manner

PRJNA286308 | ENA

Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types (RNA-seq)

We report the design and implementation of a "breakpoint analysis" pipeline to discover novel gene fusions by tell-tale transcript level or genomic DNA copy number transitions occurring within genes. We use this method to prioritize candidate rearrangements from high density array CGH dat...

ORGANISM(S): Homo sapiens

2013-05-31 | E-GEOD-45133 | biostudies-arrayexpress

Characterization of t(15;21) translocations in myeloid disorders

We report on two novel t(15;21) alterations [t(15;21)(q24;q22) and t(15;21)(q21;q22)], which led to concurrent disruption of RUNX1 and two translocation partner genes encoding for transcription factors (SIN3A, TCF12) Examination of four different patients with myeloid disorders. 2 out of 4 have been...

ORGANISM(S): Homo sapiens

2016-07-29 | E-GEOD-71551 | biostudies-arrayexpress

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